MSK Flashcards
What haem condition can predispose to pseudogout
hemochromatosis
allopurinol MOA
xanthine oxidase inhibitor
Main SE of colchicine
diarrhoea
treatment of septic arthritis
flucloxacillin/clindamycin for staph aureus 4-6 weeks
Cipro if gonorrhoea
Rheumatoid arthritis monitoring
DAS28 + CRP
most common extra-articular manifestation of RA
keratoconjunctivitis sicca
how to differentiate reactive and septic
in reactive, organism cannot be recovered from joint
specific eye conditions associated with reactive arthritis
conjunctivitis and anterior uveitis
psoriasis management
First line
1. potent corticosteroid + vitamin d analogue
Second line
1. Phototherapy (can cause SCC)
2. Oral methotrexate
Long term management of antiphospholipid syndrome
low dose aspirin (warfarin lifelong if had thrombotic event)
What can cause polymyositis and dermatomyositis
paraneoplastic syndrome
viral infection e.g. cosackie virus/HIV
Critical test for myositis
CK
What tests are done for ACL
Anterior drawer tests (ACl moves)
Lachmans (ACL moves)
Bakers cyst important differential
DVT
serious complication of baker cyst
compartment syndrome
Why do you not use steroid injections in foot
rupture of plantar fascia or fat pad atrophy
What is bechets disease
oral ulcers
genital ulcers
anterior uveitis
Why do you get AKI with compartment syndrome
accumulation fo myoglobin in kidneys
Which clinical sign points towards compartment syndrome
pain on passive stretch
How does ostechondritis dissicens present
pain after exercise
intermittent locking and swelling of joint
most common cause of death is systemic sclerosis
respiratory involvement: interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH)
Antibodies associated with systemic sclerosis
CREST: anti-centromere
Diffuse: Anti-SCL70
CREST syndrome
Calcinosis
Raynauds
oesophageal motility
sclerodactyly
telangtascia
What antibiotic should you not co-prescribe with methotrexate
trimethoprim
severe bone marrow suppression and pancocytopenia
What medication can cause drug induced lupus
isonazid
diagnostic investigation for osteomyelitis
MRI
RA x-ray findings
loss of joint space
juxta-articular osteoporosis
soft-tissue swelling
periarticular erosions
subluxation