Endo Flashcards

1
Q

Myxoedema coma symptoms

A
  • Hypothermia
  • Confusion
  • Bradycardia
  • Hyporeflexia
  • Seizures
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2
Q

do sulphonureas cause weight gain or loss

A

gain

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3
Q

amiodarone induced hypothyroidism treatment

A

continue amiodarone and start levo

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4
Q

SIADH drug causes

A

carbamazepine, sulfonylureas, SSRIs, tricyclics

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5
Q

conditions that cause hyperkalaemia

A
  • AKI
  • CKD
  • tumour lysis syndrome
  • rhabdomyolysis
  • adrenal insufficiency
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6
Q

medications that cause hyperkalaemia

A
  • aldosterone antagonists
  • ACE-I/ARB
  • NSAIDs
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7
Q

complication of anti-thyroid drugs

A

bone marrow suppression -> seek immediate medical advice

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8
Q

what must you always exclude before diagnosing hyperthyroidism

A

anxiety

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9
Q

impaired fasting glycaemia

A

a fasting plasma glucose level between 6.1 mmol/l and 6.9 mmol/l,

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10
Q

DKA diagnostic criteria

A

glucose > 11 mmol/l or known diabetes mellitus
pH < 7.3
bicarbonate < 15 mmol/l
ketones > 3 mmol/l or urine ketones ++ on dipstick

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11
Q

DKA resolution

A

pH >7.3 and
blood ketones < 0.6 mmol/L and
bicarbonate > 15.0mmol/L

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12
Q

impaired glucose tolerance

A

plasma glucose less than 7.0 mmol/l and OGTT 2-hour value greater than or equal to 7.8 mmol/l but less than 11.1 mmol/l

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13
Q

what cardiac issue can thyrotoxicosis lead to

A

high output cardiac failure + AF

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14
Q

most common cause of hyperaldosteronism

A

bilateral adrenal hyperplasia

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15
Q

pioglitazone SE

A

weight gain (rather than loss); fluid retention; liver dysfunction; and associated fractures.

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16
Q

c peptide

A

high in type 2
not affected by exogenous insulin but high in insulinoma

17
Q

causes of main endo conditions

A

cushings: pituitary tumour
hyperaldosteronism: bilatateral adrenal hyperplasia
addisons: autoimmune desctruction
hyperparathyroid: solitary adenoma

18
Q

what drug can impair glucose tolerance

A

thiazides