MSK Flashcards
What are the main functions of bone?
Weight bearing Support Protection Mineral store Blood formation
Name the 2 different types of bone
Compact (cortical) bone
Trabecular (spongy) bone
Where is red marrow found?
Spongy bone
What is the name of the membrane that covers the outside of bones?
Periosteum
what is the name of the membrane that lines the medullary canal of bones?
endosteum
What is the name of the structural units which make up compact bone?
Osteons
Name the two different types of canal in an osteon
Central vertical Haversian canal, horizontal volkmann’s canal
Describe the structure of spongy bone
Network of lamellated trabecular filled with bone marrow
What are the three main cell types in bone and what are their roles
- Osteoblasts (blast out bone matrix)
- Osteoclasts (break down bone matrix)
- Osteocytes (senses mechanical forces and regulates the other two cell types
What is the name given to the pit formed as osteoclasts break down bone?
Howships lacunae
What type of collagen is found in bone?
Type I
What is the type of crystal found in bone?
Hydroxyapatite crystals (calcium & phosphate crystals)
What disease occurs when bone reabsorption is greater than bone formation?
Osteoporosis
What disease is caused when bone reabsorption is increased?
Paget’s
What disease is caused in cases of decreased bone resorption?
Osteopetrosis