Morphology Of Formed Elements Flashcards
What type of cell do all cells start as?
Hematopoietic stem cell
What are the two cell lines that stem from HSCs?
Myeloid cell line
Lymphoid cell line
What does the myeloid cell line break down into?
Blast cells
Erythrocyte CFU/Proerythroblasts
Megakaryoblast
Myeloblast
Monoblast
What is the process of the forming of an erythrocyte?
Erythrocyte CFUs/proerythroblasts become early erythroblasts with help from erythropoietin. then become late erythroblasts which shed their nucleus. Erythroblasts then become reticulocytes which rid themselves of the rest of their organelles leading them to become erythrocytes
What is the process of the forming of platelets?
They start as megakaryoblasts which morph into megakaryocytes which are cells that undergo multiple rounds of mitosis but never split causing them to become very large. These large cells develop projections that the force of the blood stream lops off into small pieces that become platelets
Process of formation of granulocytes
Begin as myeloblasts which then become prolymphocytes
The prolymphocytes then become either neutrophil band cells, eosinophil band cells or basophils band cells.
Each then becomes their respective granulocytes
Process of formation of monocytes
Begin as monoblasts which them become promonocytes and then monocytes
Process of formation of B and T cells
Begin as lymphoblastic in the lymphoid cell line. Then become prolymphocytes and then become either T lymphocytes or B lymphocytes
Stem cells
Able to become multiple types of formed elements
Hematopoietic stem cells
Myeloid cell line
Lymphoid cell line
Committed cells
Committed to a particular developmental pathway
Myeloblasts
Monoblasts
Lymphoblasts
Precursor cells
Immature leukocytes
Promyelocyte-> band cells
Promonocytes
Prolymphocytes
Mature leukocytes
Functional cells that enter the blood and stay in circulation or migrate to tissues
Neutrophils Eosinophils Basophils Monocytes B/T lymphocytes
