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dr taher classes HK > monoclonal antibodies > Flashcards

monoclonal antibodies Flashcards

1
Q

Palivizumab

A

RSV fusion protein —- only prophylaxis

premature high risk infants

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2
Q

infliximab
adalimumab
certolizumab
golimumab

A

TNF alpha inhibitor

must do TB test

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3
Q

TB test must be done for

A

TNF alpha inhibitors and etanercept (decoy rec)

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4
Q

natalizumab

A

alpha 4 integrin —- multiple sclerosis

increase risk for PML by jc virus (polyoma DNA )

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5
Q

Eculizumab

A

C5 complement protein (PNH)

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6
Q

ustekinumab

A

IL 12 IL 23 —- psoriasis/ psoriatic arthritis

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7
Q

alemtuzumab

A

CD52 (CLL)

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8
Q

Muromonab

A

CD3 — T cell marker — when you dont want a t cell response like in transplants

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9
Q

bevacizumab / ranibizumab

A

anti VGEF —- diabetic retinopathy

bevacizumab — colon cancer
NSLC

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10
Q

Omalizumab

A

igE asthma

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11
Q

baciliximab

daclizumab

A

IL2R

CD25

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12
Q

Ocrelizumab

Rituximab

A

CD 20
ocre —- MS
ritux—- non hodgkin lymphoma CD20

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13
Q

abciximab

A

gpIIb III —- prevents platelet agg

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14
Q

Denosumab

A

RANK L —- osteoporosis

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15
Q

atezolizumab
avelumab
darvalumab

A

programmed death ligand

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16
Q

pembrolizumab

nevolumab

A

programmed death receptor

17
Q

ipilimumab

A

CTLA4

18
Q

tocilizumab

A

IL6

19
Q

idarucizumab

A

dabigatran reversal

20
Q

alirocumab

evolocumab

A

PCSK 9 inhibitor— degrades LDL rec

dr taher classes HK (24 decks)

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