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dr taher classes HK > cvs 12 > Flashcards

cvs 12 Flashcards

1
Q

D actinomycin MOA

A

anti cancer

RNA polymeras II

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2
Q

cox 2 physiological and pathological function

A

PHYSIOLOGICAL
renal perfusion
tissue repair

PATHOLOGICAL
inflammation and pain

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3
Q

large vessel vasculitis

A

GTA

takayasu

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4
Q

medium vessel vasulitis

A

PAN
buerger
kawasaki

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5
Q

GTA most common in ?

A

females 60 yrs

branches of carotid artery

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6
Q

symptoms of GTA

A 
fatigue fever malaise
jaw claudication
unilateral headache
ischemic OPTIC NEUROPATHY
polymyalgia rheumatica
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7
Q

diagnosis GTA

A

intimal layer thickening
FOCAL GRANULOMATOUS inflammation

segmental vasculitis so the wall looks normal

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8
Q

PMR

A

muscular pain and stiffness
shoulder and hip girdle
pain is WORSE IN MORNING and WORSE WITH activity

creatinine kinase NORMAL

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9
Q

steroids induced myopathy

A

progressive PROXIMAL musculoskeletal weakness
NO pain + atrophy of muscle
mostly involves LOWER extremity

creatinine kinase NORMAL

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10
Q

Polymyopathy (cd8)

dermatomyopathy (cd4)

A

proximal muscular weakness
arthritis can be +ve
dermatomyositis —- skin rash

Creatinine kinase is increased

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11
Q

hypothyroid myopathy

A

delayed reflexes
proximal muscular pain

creatinine kinase INCREASED

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12
Q

statin induced myopathy

A

proximal muscle pain and weakness
wks to months

CK iINCREASED

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13
Q

statins + fibrates SE

A

myopathy

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14
Q

statins + niacin

A

myopathy

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15
Q

fibrates + bile acid resins

A

gall stone

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16
Q

depression anxiety musculoskeletal pain and fatigue more than 3 months
multiple tender joints

A

fibromyalgia rheumatica

17
Q

levels of ESR CRP in FMR

A

NORMAL

18
Q

FMR age group

what form of exercise helps them

A

young females 20 -55

aerobics help them

19
Q

txt for FMR

A

TCA —– amitryptilline imipramine desipramine clomipramine

SNRI —– duloxetine venlafaxine

20
Q

txt for diabetic neuropathy

A

amitryptalline

duloxetine

21
Q

which drug shd be avoided in elderly

A

AMITRYPTILLINE

dr taher classes HK (24 decks)

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