Monobactams Flashcards

1
Q

What is the only available monobactam in the market?

A

Aztreonam

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2
Q

(T/F) - Monobactams are safe to administer to patients with allergies to other beta-lactams

A

TRUE

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3
Q

(T/F) - A patient with an allergy to ceftazidime can use aztreonam as an alternative

A

FALSE - if a patient is allergic to ceftazidime, aztreonam cannot be given due to cross-allergenicity (vice-versa)

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4
Q

Monobactams have a good spectrum over which bacteria?

A
  • Pseudomonas

- Most other GNRs

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5
Q

(T/F) - There is a high incidence of hypersensitivity of monobactams

A

FASLE - low incidence

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6
Q

Is it recommended to add aztreonam with another beta-lactam against the same organism?

A

No, it’s unwarranted

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7
Q

What is recommended to add with aztreonam as an empiric therapy in what types of infections?

A

Add another non-beta-lactam drug for serious nosocomial infections

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8
Q

What are the main utilizations of monobactams?

A
  • Gram (-) infections
  • Pseudomonas
  • Pt is allergic to beta-lactams
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9
Q

What should be done if a patient presents with an anaphylactoid reaction with beta-lactam drugs but cannot be determined if it was an allergic reaction to ceftazidime?

A
  • Proceed with caution with aztreonam
    OR
  • Use an alternative agent
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