Monobactams Flashcards
What is the only available monobactam in the market?
Aztreonam
(T/F) - Monobactams are safe to administer to patients with allergies to other beta-lactams
TRUE
(T/F) - A patient with an allergy to ceftazidime can use aztreonam as an alternative
FALSE - if a patient is allergic to ceftazidime, aztreonam cannot be given due to cross-allergenicity (vice-versa)
Monobactams have a good spectrum over which bacteria?
- Pseudomonas
- Most other GNRs
(T/F) - There is a high incidence of hypersensitivity of monobactams
FASLE - low incidence
Is it recommended to add aztreonam with another beta-lactam against the same organism?
No, it’s unwarranted
What is recommended to add with aztreonam as an empiric therapy in what types of infections?
Add another non-beta-lactam drug for serious nosocomial infections
What are the main utilizations of monobactams?
- Gram (-) infections
- Pseudomonas
- Pt is allergic to beta-lactams
What should be done if a patient presents with an anaphylactoid reaction with beta-lactam drugs but cannot be determined if it was an allergic reaction to ceftazidime?
- Proceed with caution with aztreonam
OR - Use an alternative agent