General Aspergillus Infections Flashcards
1
Q
Which Aspergillus spp accounts for more than 90% of most clinical invasive infections?
A
A. fumigatus
2
Q
What is the pathophysiology of Aspergillus spp?
A
Produce conidia; once inhaled, growth results in pulmonary inflammation, tissue destruction, and potential dissemination into other organs
3
Q
(T/F) - Invasive Aspergillus is considered an opportunistic infection
A
TRUE - needs impaired host defense to cause disease
4
Q
What other two Aspergillus spp are common to cause invasive infections?
A
- A. flavus
- A. niger
5
Q
Allergic bronchopulmonary aspergillosis (BPA) is caused by which Aspergillus spp?
A
A. fumigatus
6
Q
How is allergic BPA clinically presented?
A
- Severe asthma with wheezing
- Fever
- Weight loss
- Malaise
- Chest pain
- Productive cough with blood tinged sputum
7
Q
How is allergic BPA treated?
A
Itraconazole
