Module 9 (part of test 4) Flashcards
Leukemia is characterized according to cell ______ and ______
type maturation (age)
What Leukemia is most common in children?
Acute Leukemia
Which Leukemia has a large number of MATURE WBC’s?
Chronic
Acute Leukemia has a large number of ______ WBC’s?
immature
What is the 7th most common malignancy?
Lymphoma
What are the 3 types of Lymphomas?
Hodgkins
Non-Hodgkins
Burkitt’s
Non-Hodgkins Lymphoma is a disorder of the _____ and _____ cells?
T
B
Burkitt’s Lymphoma is an aggressive _____ Cell proliferation?
B
A patient with Burkitt’s may have what on their mandible?
osteolytic lesions
If we are seeing a patient with a WBC disorder we need a ________ and possibly ______ before treatment?
MD consult
premedication
What is the most common causes of urticaria in adults and in kids?
Adults- drugs
Kids- food
What are the 3 most common causes of anaphylactic death?
bee sting
wasp sting
penicillin
Allergic reactions result from a _______ reaction to a _______?
immune
antigen (non-infectious)
What cells process the presence of an antigen?
T-lymphocytes
Macrophages
What cells recognize the antigen and are the primary lymphocyte in humoral immunity?
B-lymphocytes
B-cels make what 2 things?
Plasma cells
Memory B-cells
Plasma cells make?
antibodies (immunoglobulins)
What type of hypersensitivity involves the humoral immunity and occurs soon after the 2nd contact/exposure?
Type 1
Type 1 Hypersensitivity is _____ mediated?
IgE
What is the most serious type 1 allergic response?
anaphylaxis
What 2 substances in L/A could a patient be allergic to?
Parabens
Sulfites
What medication generally doesn’t cause a true allergic reaction?
Codeine
What was the 1st generation Antagonist medication used in the treatment of allergic reactions?
Benadryl
What was the 2nd generation Antagonist medication used in the treatment of allergic reactions?
Allegra, Claritin, Zyrtek
Flonase, Nasonex, and Rhinocort are examples of?
Intranasal Glucocorticoids
What immune system is referred to as “delayed”
Cellular
What cells play the central role in cellular immunity?
T-lymphocytes
T-cells produce?
cytokines and memory t-cells
The ______ is the largest organ. It weighs ____ lbs and is located in the ______Quadrant?
liver
3
UR
A compromised liver means a decreased synthesis of _________ factors?
coagulation
What are 3 causes of hepatitis?
virus
Acetaminophen
Alcohol
Hepatitis A is transmitted through what route?
fecal - oral
Does Hepatitis A have a carrier state?
No
Is there a vaccine for Hepatitis A?
yes- harrivax
How is Hepatitis B transmitted?
Blood (direct/indirect contact)
_________transmission of Hepatitis B is NOT important
airborne
Hepatitis B has a ____ onset and _______duration compared to Hepatitis A
slower
longer
A Hepatitis B immunoglobulin shot can be administered how long after exposure?
24-48 hrs
Is there a Hepatitis C vaccine?
no
What is the most chronic blood borne infection in the U.S.
Hepatitis C
Hepatitis _____ only occurs in the presence of Hepatitis B?
D
Hepatitis ______ only occurs in the presence of Hepatitis C?
G
Icteric means? and is due to?
Jaundice
billirubin buildup
What precedes the onset of jaundice?
Pre-icteric phase (prodromal)
The post-icteric phase is _________ and can last how long?
convalescent
6 mo
_______ _________ liver is when hepatocytes get engorged with fatty lobules and distend?
Fatty Infiltrate
______ _______ is when the liver goes through destructive cellular changes?
alcoholic hepatitis
_______ is a progressive fibrosis of the liver and is irreversible?
cirrhosis
If surgical procedures are necessary for hepatitis patients we need to have ______ ability evaluated?
clotting
_______ is an alcohol sensitizing drug which increases the effects of a hangover?
Antabuse
What drug works like antabuse but is safer?
Temposil
How much hydrochloric acid do we produce a day?
2 liters
A well defined break in the GI mucosa is called a?
peptic ulcer
Most ulcers are located in the?
duodenum/stomach
1st degree relatives have a _____risk of GI ulcers?
3 fold
What is the main cause of GI diseases?
Overproduction of Acid
What is the 2nd cause of GI diseases?
H-pylori bacteria
Stomach discomfort occurs how long after eating?
90min-3hrs
What are 3 common drugs used in the treatment of H-pylori bacillus GI disorders?
Amoxicillin
Biaxin
Zantac
Pepto-bismol, Tums, Zantac, and Tagamet are OTC drugs that _____ of gastric secretions?
raise PH
What OTC GI medication interfered with lidocaine and valium typically used in dental treatment?
Tagamet
We need to avoid _____ and ______ OTC drugs when someone is taking GI medications?
Aspirin
NSAIDS
Antacids may impair the absorption of what 2 antibiotics?
Tetracycline
Erythromycin
What are 2 common oral complications with GI disorders?
Oral Candidiasis ( due to antibiotics) Enamel Erosion (due to vomiting)
What GI disease is Serious and sometimes fatal and occurs from prolonged antibiotic use?
PC- pseudomembranous colitis
Pseudomembranous Colitis is an overgrowth of?
Clostridium Difficile
Broad Spectrum antibiotics cause _____ after taking them for 4-10 days?
diarrhea
You should discontinue broad spectrum antibiotic use and switch to ____ or _____ with GI disorders?
Flagyl
Vancomycin
Plavix alters ______ function?
platelet
What is the most common inherited bleeding disorder?
Von Willebrand’s
Hemophilia A is a deficiency / defect of factor?
8
Hemophilia B is also known as ____ and is a deficiency of factor _____?
Christmas Disease
9
What medications do we recommend for dental management in patients with bleeding disorders?
Acetaminophen with/out Codeine
`Aspirin therapy results can last how long after the patient stops taking it?
9 days
Anemia is associated with _____ of RBC’s
number
A normal RBC is ___% hemoglobin?
33
The _____ is the sensor that determines the level of oxygenation of RBCs
Kidney
Low oxygenation in RBCs tells the kidney to produce?
erythropoietin
What is the most common Anemia?
iron deficiency
Pernicious Anemia is a lack of ________ factor which is secreted from the _____ Cells?
intrinsic
parietal
What is a genetic anemia most commonly found in African Americans?
Sickle Cell
Radiographically the bone appears with ______ trabeculae arranged in a ______ pattern like a “_____ ____” in sickle cell patients?
widened
horizontally
step ladder
Patients with sickle cell disease need an oxygen saturation of _____%
95
Sickle cell patients _____ use Nitrous?
can
Nitrous levels need to be at ______% oxygen for sickle cell patients?
50 or higher