Module 10 (part of test 4) Flashcards
Penicillins have a ___ _____ _____ structure?
beta-lactam ring
Penicillins interfere with?
bacterial cell wall synthesis
Narrow spectrum antibiotics are effective agains what bacteria?
gram -
Gram + bacteria have an increased _____ in their cell wall?
peptidoglycan
Penicillin resistant bacteria produce?
B-lactanase
What is added to penicillin to restore its effectiveness against resistant strains?
Clavulanate
Amoxicillin + Clavulanate = _________
Augmentin
What is the prototype natural penicillin?
Penicillin-G
NAme 1 Narrow spectrum NATURAL penicillin?
Penicillin-V
You should take narrow spectrum antibiotics with ______ to protect your GI and with ______ to protect your esophagus?
yogurt
water
Amoxicillin and Trimox are examples of?
broad spectrum antibiotics
What drug has a broader range than penicillins and has similar actions?
cephalosporins
What is the 1st Generation cephalosporin?
Keflex
What is the name of the 2nd Generation cephalosporin and what is the difference from the 1st generation?
Ceclor
affects gram - also
What is the name of the 3rd Generation Cephalosporin? What makes it special?
Rocephin
Used in conjunction with L/A
Is a broad gram (-)
What Cephalosporin is used in the treatment of MRSA?
Maxipime
Cephalosporins affect _____ bacteria, NOT _____
aerobic
anaerobic
What medication is good for the treatment of dental infections?
penicillin
What medication is effective STRICTLY fro Anaerobic bacteria?
Nitroimadazoles
What nitroimadazole is used widely in dentistry?
Flagyl
We should avoid giving out ______ when a patient is on Flagyl?
alcohol mouthrinses
What broad spectrum medication inhibits DNA replication?
Quinolones
What are 2 Quinolones used as outpatient antibiotics?
Lipro
Levaquin
What medication is given to patients who are allergic to penicillin?
Z-pack (erythromycin)
What medications are bacteriostatic and similar to erythromycin?
Macrolides
Name 2 types of Macrolides?
Zirhromax
Biaxin
What Macrolide is used in the treatment of Periodontal Disease?
Zithromax
What medication inhibits the production and secretion of collagenase by the PMN’s
Tetracyclines
What medication is indicated for CHRONIC periodontal disease?
Doxycycline (20mg) * Periostat *
What is the name of the topical doxycycline?
Atridox
Why is doxycycline so good in the treatment of Periodontal Disease?
has a high affinity for gingival crevicular fluid
Kids age ______ and under shouldn’t take tetracycline?
8
What affect does Demerol have when given to kids?
excitability
reverse side effect
Analgesia means?
pain reduction/relief
Is pressure still felt with analgesia?
yes
Anesthesia means?
Lack of sensation (L/A)
______ usually accompanies anesthesia?
Analgesia
Stage 1 = _________
The patient ______ conscious during this stage?
Analgesia
Is
What terminates stage 1?
Loss of consciousness
What medication used in dentistry maintains stage 1?
Nitrous
Stage 2 = _______/________
This stage initiates _____ but can have involuntary movements?
delirium/excitement
unconsciousness
Stage 3 = ________ ________
surgical anesthesia
Stage 4 = _________ ______
respiratory paralysis
General Anesthesia is ______ lack of awareness?
total
Most drugs work on what part of the brain?
cerebral cortex
Local anesthesia works by blocking nerve impulses at _____ _______ by blocking _____ ______?
cellular level
sodium channels
What is the most common form of sedation?
IV
What are 2 common agents used in the induction phase of general anesthesia?
Pentothal
Propofol
What paralytic drug is used when patients get intubated or are very combative?
Succinylcholine
What is the most common type of psychosis?
Schizophrenia
How did “older” typical antipsychotics work?
blocked dopamine receptor sites
Name 1 “older” antipsychotic drug?
Thorazine
What atypical antipsychotic is used in the 1st line of therapy for Schizo/Bipolar patients?
Risperdal
Name 2 common atypical antipsychotics?
Abilify
Clozaril
What are 2 common side effects of antipsychotic medications?
Parkinson movements
Tardive Dyskinesia
Anticholinergics produce symptoms of ______, _______ and _______ dentally?
xerostomia
root caries
oral candidiasis
Depression Diagnosis is based on?
5 symptoms or more…every day…. for 2 wks
What are 3 classes of anti-depressants?
MAOI’s
TCA’s
SSRI’s
MAO inhibitors inhibit ______ _____ so it wont break down catecholamines?
Monoamine Oxidase
What is the most potent antidepressant?
MAOI’s
Name 2 common MAO inhibitors?
Nardil
Marplan
What antidepressant inhibits the re-uptake of NE/Serotonin?
TCA
What dental condition do TCA’s help relieve?
Nocturnal bruxism
What are 2 commonly used TCA’s?
Elavil
Tofranil
TCA’s have been replaced by?
SSRI
What antidepressant inhibits ONLY serotonin re-uptake?
SSRI
What was the prototype SSRI?
Prozac
What are 3 commonly prescribed SSRI’s?
Paxil
Zoloft
Wellbutrin
ADHD is due to increased release of ____ and ______?
NE
Dopamine
What is the GOLD STANDARD mood stabilizer?
Lithium
What is an example of a Somatoform Disorder?
Anorexia
What type of drug is widely prescribed for anxiety?
Benzodiazepines
Can we use L/A with epi if a patient is on Benzodiazepines?
yes
What is the prototype Benzodiazepine?
Valium
Which Benzodiazepine has an antagonist? What is the name of the antagonist?
Versed
Romazicon
Valium _________ anesthesia while Versed is used in _______ sedation?
induces
preoperative
Name 3 oral Benzodiazepines?
Valium
Xanax
Librium
What is the Benzodiazepine used as a date rape drug?
Rohypnol “roofies”
Ambien and Lunesta are what type of drug? What class?
Benzo-like (used for insomnia)
Class IV- Rx needed
Name 3 Barbiturates used to induce anesthesia?
Pentholal
Pentobarbital
Phenobarbital
What sedative/hypnotic did Michael Jackson die of?
Propofol
Propofol has a ______ induction time and a ______ duration?
rapid (40sec)
short (5-10min)
What Non-Bartbiturate did Anna Nicole Smith OD on?
Noctec
Noctec has a _____ onset time and a _______ duration?
long (30-60min)
long (4-6hr)
What Non-Barbiturate sedative/hypnotic is safer because it has an antagonist? What is the name of the antagonist?
Miltown
Narcan/Maxicon