Module 2 (part of test 1) Flashcards
The autonomic nervous system controls _______ responses?
involuntary
What are the 2 divisions of the Autonomic Nervous System
Sympathetic
Parasympathetic
“Rest and relaxation” deals with what branch of the autonomic nervous system?
Parasympathetic
The Sympathetic division prepares the body for “________ or ________” responses?
fight
flight
What is the receptor that deals with the Sympathetic Division?
Adrenergic
What is the receptor that deals with the Parasympathetic Division?
Cholinergic
Which receptor has divisions and what are they?
Adrenergic
Alpha and Beta
ANS drugs are used in dentistry. What are two examples?
Anesthetic
Nitrous Oxide
What ANS drugs can cause Xerostomia by blocking acetylcholine receptors?
Anticholinergics
Anti-depressants and Anti-psychotics have effects _______ to ANS system?
similar
The somatic nervous system stimulates ______ responses?
voluntary (skeletal muscles)
The Sympathetic nervous system dilate pupils when activated…This dilation of pupils is called?
Mydriasis
What 3 things does a Synapse consist of?
presynapse
synaptic cleft
postsynapse
What is the term for a group of nerve cell bodies located outside the Central Nervous System?
Ganglia
What are the 4 parts of a Neuron?
Cell Body
Dendrite
Axon
Axon Terminal
What carries the signals between neurons/other cells?
A neurotransmitter
What are the 3 catecholamines of the Adrenergic response system?
Epi
Nor-epi
Dopamine
Catecholamines come from the _______ ______ and are put into the blood during sympathetic stimulation?
Adrenal Medulla
The Sympathetic Response has _______ receptors like Adrenaline?
Adrenergic
The Alpha Receptors of the Sympathetic Response are responsible for _______?
smooth muscle relaxing
What are the 2 divisions of the Beta-receptors of the Sympathetic response are?
Beta 1
Beta 2
__________ receptors of the sympathetic response are responsible for the heart muscle?
Beta 1
Beta 2 receptors of the sympathetic response are responsible for the _____
lungs
Cholinergic Receptors are found in the _______ response system?
parasympathetic
Cholinergic receptors of the parasympathetic response have _________ receptors on them?
acetylcholine
What receptors of the parasympathetic response are responsible for most side effects?
Muscarinic
Muscarinic receptors ________ Heart Rate?
decrease
What receptors have to do with muscular paralysis like in general anesthesia?
Nicotinic
What receptors are sensitive to Nor-epi and epi?
Alpha 1 Adrenergic (sympathetic)
Alpha 1 Adrenergic receptors have an excitability concept that_________vessels?
constrict
Due to the response of Beta-1 Adrenergic receptors the heart needs?
more Oxygen
Stimulation of the Beta 2 Adrenergic receptors causes smooth muscle _______ Vaso________ and Broncho_______?
relaxation
dilation
dilation
If someone is in Anaphylactic Shock what do we give them to dilate their bronchi?
epinephrine
What receptors of the parasympathetic are found in smooth muscle, cardiac muscle, and glands?
Muscarinic Cholinergic
Muscarinic receptors of the parasympathetic response cause smooth muscle ______ and _______ cardiac function and glandular secretions
contraction
slows
What does Sympathomimetic mean?
drug that mimics sympathetic nervous system
Another name for a sympathomimetic is?
Adrenergic Agonist
An agonist ________ something?
promotes
Another name for a Cholinergic Agonist is?
Parasympathomimetic
A sympathomimetic stimulates ________ nervous system?
sympathetic
The effects of a adrenergic agonist depends on?
Alpha and Beta adrenergic receptors
________ has a limited use as a vasoconstrictor in Local Anesthetic?
Limited
Epinephrine affects alpha adrenergic receptors and causes vaso________ which _______ B.P.
constriction
increases
Epinephrine affects beta-1 adrenergic receptors and causes an increase in the ______ and ______ of the heart?
strength
rate
Epinephrine affects beta-2 adrenergic receptors and causes ___________
bronchodilation
What drug is used in ophthalmology to cause Mydriasis?
Ephedrine
What is a common alpha adrenergic drug used as a nasal decongestant?
phenylephrine
What OTC drug is used to “cook” Meth?
Sudafed
Pseudoephedrine is a _____ and ______ _______ drug?
alpha
beta
adrenergic
What drug is a precursor of Nor-epi and epi?
dopamine
Dopamine is used primarily for shock and in what disease?
Parkinsons (lack of dopamine)
what was the first bronchodilator that affected both beta adrenergic receptors?
isoproterenol
what is the bronchodilator of choice now?
ALBUTEROL (ventolin brand name)
it doesn’t react with beta 1 receptors (heart)
What are some side effects of adrenergic drugs?
CNS disturbances
heart arrhythmia
heart palpitations
hypotension
alpha blocking drugs cause non-selective ________ which decreases ______?
vasodilation
BP
alpha blocking drugs result in ____ and ______ _______?
tachycardia
orthostatic hypotension
Alpha receptors are found on the ________ and when stimulated by epi/nor-epi they ______
arteries
constrict
phenoxybenzamine/Dibenzyline is used to treat _______ syndrome and ______ in newborns
raynaud’s
pulmonary hypertension
Raynauds syndrome is an ______ disease that is triggered by ________ which causes arterial ________
autoimmune
cold
vasoconstriction
Beta blocking generic drugs all end in _______ suffix?
olol
Beta Blockers block increased _______ broncho__________ and ______
heart rate
dilation
tachycardia
Which beta blocker isn’t ok to use epinephrine Local Anesthetic on? Why?
Nadolol (Corgard)
because it is nonselective (affects beta 1 and 2 receptors)
Propranolol is a _____ beta blocker used to treat many diseases and can cause ________ as well?
non-selective
bronchoconstriction
What 2 beta blockers are beta 1 specific?
Metoprolol
Atenolol
Neuronal Blocking Drugs block _______ from the sympathetic neuron which causes decreased BP?
release of Nor-epi
What is a very strong Neuronal blocking drug used to treat hypertension?
Alpha-Methyldopa (Aldomet)
What drug has an antidepressant effect on the CNS by inhibiting alpha receptors in the medulla?
Clonidine (Catapres)
Clonidine is used to tx what?
ADHD
Alcohol/Opiate withdrawal
Anxiety/Bipolar
Newer neuronal blocking drugs are causing _______ in order to decrease BP
vasodilation
Cholinergic drugs either stimulate _______ receptors or bock ___________
muscarinic
acetylcholinesterase
What drug is synthetically made and mimics acetylcholine?
Choline Esters
Anticholinergic drugs can either _____ or _____ effect of Acetylcholine?
prolong
block
What drug is a prototype anticholinergic that decreases salivary flow and GI spasm which is good prior to dental surgery?
Atropine