Module 8 Wk 2 Flashcards
what are the 2 functional divisions of the ANS?
The parasympathetic and sympathetic
What is the other anatomical word for the parasympathetic system?
craniosacral system
what is the other anatomical name for the sympathetic system?
thoracolumbar system
What is the function of the parasympathetic division?
Day to day control of viscera
what is the function of the sympathetic division?
Active when the animal is stressed
In relation to the para and sympatheric systems what in organs is determined?
Organ function determined by the balance of input from each system
What are the two anatomical divisions of the ANS?
The CNS and the PNS
where are the main control centres of CNS located?
Hypothalamus and the midbrain
Can cerebral cortex command the control centeres?
No - They can influence
eg emotional status causing blushing
Where do the CNS decending fibers go?
Brainstem and spinal cord
In the PNS where is the outflow of the parasympathertic and sympatheric innervation?
The para outflow is via brain stem and sacral cord
The sympathetic outfloe is via thoracolumbar cord
What is the main difference in the two fibres (parasym and sym) in the PNS?
In the parasympathetic fibers the ganglia is closer to the organ they are innervating whereas in the sympathetic the ganglia is further away from the organ with a longer post-synaptic fibre
Where are the 3 different location of the neural cell body and for what kind of cell body?
- Dorsal horn for sensory cell bodies
- ventral horn for motor striated muscle
- Intermediate/lateral horm for motorneuron cell bodies of ANS in thoracolumbar and sacral cord
How do the parasymapthetic fibres innervate all viscera?
- Cranial nerves from brain
- Segmental spinal nerves from sacral spinal cord
What cranial nerves are in volved in parasympatheic fibers innervating the viscera?
- To the head via 3, 7 and 9
- To the cervical, thoracic and abdominal viscera via cranial nerve 10
What do the sacral spinal nerves innervate?
The pelvic viscera
How do sympathetic fibers innervate all viscera?
Thoracolumbar outflow from CNS
What sympathetic fibers innervates the thoracic, abdominal and pelvic cavity and the head?
Thoracic - sympathetic chain of nerves and paravertebral ganglia
Abdominal and pelvic - fusion of fibers to form prevertebral ganglia
Head - supplied by spinal nerves from C8-T7 via vagosympathetic trunk
What carries presynaptic sympathetic fibers to the sympathetic trunk in spinal segments T1-L2?
The white rami communicans
What carries post-synaptic sympathetic fibers from the sympathetic trunk to all spinal nerves?
The grey rami communicantes
Where do the preganglionic fibers of the sypathetic supply to the head synapse?
The cranial cervical ganglion
What are the two routes for the post-synaptic fibers of the sympathetic supply to the head and neck?
- Some follow arteries in the head region
- Some follow cranial nerves 9 to 12, vagal nerve branges to the laranx and pharynx
What is the function of the post-synaptic fibers of sympathetic supply?
To innervate smooth muscle
what happens to the vagus and sympathetic trunk at the chest enterence?
Near the middle cervical ganglion at the first rib the vagus and sympathetic trunk split
Why do the vagus and sympathetic trunk split?
To pass around the subclavian artery forming the Asna subclavia
T/F the lumbar region of the sympathetic trunk supply pre and post synaptic fibers to the abdominal and pelvic regions?
True
The parasympatetic supply to the body otherwise known as the craniosacral system whats a cranial and sacral orignin, describe these?
Cranial origin is nerves 3,7,9 and 10 and the sacral orignin is S1-3 spinal cord segments
What is the oculomotor nerve (CN 3) ganglion?
Ciliary ganglion
What is the function of the oculomotor nerve?
- Targets ciliary muscles regulating lens curvature
- Targets muscles of the iris to allow pupil constriction
what arterygopalatinee the two ganglions related to the facial nerve?
Pterygopalatine, sublingual and madicbular
What is the target organ from the Pterygopalatine?
Lacrimal, nasal and palatine glands for secretion and vasdilation
What is the target organ for the sublingual and mandibular ganglion?
Sublingual and mandibular glands for secretion and vasodilation
What does the glossopharyngeal nerve aid with?
Swallowing function
What is the target organ of the ganglion assocaited with the vagus nerve?
Parasympathetic supply to neck, thorax and abdomen and majority of body viscera
What are some of the responses of the vagus nerve innervating these target organs?
- heart rate
- peristalsis
- sweating
- larynx opening
Describe how vagus nerve travels?
- Comes out of brain stem
- Runs down the neck in the vagosympathetic trunk
- back up to larynx
What arises from the vagus at the middle cervical ganglion and what do they do next?
- recurrent laryngeal nerves arise
- Run back up the neck
what do the recurrent laryngeal nerves supply?
The trachea and the cervica oesophagus
what happends ro the right and left vagus just after root of the lung (oesophagus)?
They split into dorsal and ventral branches
Describe the parasympathertic supply to the pelvic viscera?
- presynaptic fibre axons travel in pelvic nerves
- synapse at terminal ganglia
- postsynaptic fibres distribute to the pelvic viscera, lower intestinal cavity and reprodutive organs
describe how the symapthetic innervates the eye?
- The first order newuron comes from brain through brainsetem down spinal cord and exits at the T1-T3 segments
- Enters into vagosympathetic trunk as second order neuron
- Synapses in cranial cervical gnaglion medial to tympanic bulla
- continues as the third order neuron to the eye
What at the level of the eye does the sympathetic supply?
The smooth muscle of the orbit and the iris dilators
What is it called when there is loss of sympathetic input to the head?
Horners syndrome
what are clinical sign of horners syndrome?
- pupillary constriction (miosis)
- prolapse of third eyelid (cherry eye)
- narrowing of the palpebral fissure
- Enophthalmos - which is your eye sinking deeper into socket
What are examples of underyling diseases of horners syndrome?
- disc herniation (neck)
- middle ear infection (otitis
Describe how the parasympathetic innervated the eye?
- Retina recieves light and gives info to optic nerve
- Next location is the optic chiasm where there is some cross over
- From the optic chaism there is teh optic tract that leads to the pretectal nucleus
- From the pretectal nucleus to the cranial nerve 3 parasympathetic nucleus
- From here infor travels up to ciliary ganglion which they innervates from here the eye
what is a dysfunction of the oculomotor nerve?
pupil dilation not responsive to light
What is anisocoria?
One eye smaller than other
If the left eye constricts when shine a light in the eye and right eye is also constricted is it para or symp?
Sympathetic as it cause dilation
Describe what can be see with a brain herniation?
- often see miosis initially
- midbrain swelling causing compression of cranial nerve 3 and a non functioning parasympathetic nucleus of cranial nerve 3 causing mydriasis
Describe the sympathetic innervation of the urinary tract?
Storing of urine via the hypogastric nerve which comes out about L1-4 in dogs and L2-5 in cats causeing detruser relaxion to allow filling and contration of the smooth muscle at the neck of the bladder to hold it in
Describe the parasympathetic innervation of the urinary tract?
For voiding urine via the the pelvic nerve that comes out about S1-3 and contract detruster muscle to allow release
Describe the somatic innervation of the urinary tract?
Via the pudendal nerve coming out about S1-3, it contracts the straiated sphincter muscle for urinary retention
What else does the somatic innervate?
The anal sphinter which controls the perineal reflex
what are the 3 branches of ethics and define them?
- personal ethics - right and wrong we decide for ourself
- society ethics - wide agreement forming laws
- professional ethics - special situations like medical ethics
Describe the opinion that animals have no moral standing
This view arises from the contract of mortality so liek ad people we can stand up and be heard and animals cant be a part of the agreement they dont have any rights or moral standing
Describe the opinion that animals have instrumental value?
This means that we have indirect duties towards them meaning that their value arises through their value to human
Describee the opinion that animals have intrinsic value?
Means we have direct dutues towards them meaning they ahve the capiabliity to feel and it would be unacceptable to hurt dog as the dog will suffer anf thsi matters in itself
T/F others are obligated to respcet interests that flow from animals feelings?
True
what is the definition of sentience?
The capacity to feel such as sensation or emotions
what would an animal need to do to be self conscoius?
Need to be able to think about itself and its own emotions and sensation rather than simply experiencing them
what are the 2 statagies for defending the view that animals are sentient?
Inferential and non-infrential
Define Inferntial
Inference from behaviour and neuro similarity and evolutionary continuity - problem is that you gte further away from humans with animal behavoiurs so hard to argue
Define the non-inerential argument
Knowledge of animal consciousness derives directly from our interactions with animals as conscious beings - also becomes more weak as we move away from mammals
what are the two stratagies for defending the view that animals are not sentient?
- behavioural comparisons
- higher order definition of consciousness
Describe the behavioural comparisons argument for non sceintent?
This is where they belive anaimals behaviour is automatic so not learned however there is lots of evidence if a very complexed learning capability
Describe the argument of higher order definition of consciousness argument for non sentient
This is where they believe phenomenal consciousness requires the capacity to think about ones own thoughts - prblem with this is that this level on concsciousness has not been proved to be needed for scientience
describe a mouse interms of sentuence and moral standing
- pest = no moral standing
- lab animal = instrumental value
- pet = intrinsic value
From a conteactaianisms point of view why should we act morally?
Its in your self intrest - like showing consideration is for your own sake
What do contractarains think about animals?
Due to the contactarain view being based off of agreement they do now believe animals neither create nor ahve moral duties because they cant agree
So as a contractarian any form of animal use is acceptable?
Yes
When would use of animals be ethincally desirable in a contractarians eyes?
If it benifits humans
Why might a contractarian have an indirect eithical obligation towards animals?
Due to them mattering to humans
What is an utilitarianism viw on any being suffering?
That there is no moral justification for refusing to take that suffering into consideration
How do utilitarians view animals?
Like humans they deserve moral consideration - in deciding what to do we must consider welfare consequences for animals as well as benifits to humans and animals (COST BENIFIT)
what do utilitarians think about killing animals (like for food)?
Justified if the farming conditions are not detrimental to animal welfae and the killing is humanely performed
What is the problems with the utilitarianism view?
- How so we weight the intrests for wach party? how do we know the strengths of the intest for animals
- cant really compare killing a human and an animals due to the questions like - why kill and innocent human if its going to be replaced by another living a better life - we think this about dogs and pets all time but most would not agree this can apply to humans
How does the animals right view percieve animals being used?
They believe it is unacceptable to treat a sentient being as a means to achieve a goal - no benifit can justify the violation of the right of the animal
what are the 3 types of increasing stregth of animal rights?
- The moral-status sense where the animals have at least some moral status and dont exist soley for humn use so they should be treated well for their own sake
- The equal-consideration sense where we must give equal moral weight to human and animal interest
- The utility-trumping sense where like humand animals ahve certain vital interests that we must not over ride
What are problems with the animal right view?
- we cannot protect prey without at the same time neg effecting predtors
- cant combine respect for rats and amice whilst also protecting human health
What are the 3 components of pain?
- sensory-discriminative component that refers to the capacity to analyse loaction, intensity and duration of the nocieptive stimulus
- A motivational and affective component that gives rise to the unpleaseant charater of pain perception and modifies behavoiur
- A cognitive and evaluative component involved in the phenomena of anticipation, attention, suggestion and past experiences.
what are the factors of the criteria of paIn?
Suitably complex nervous system
Protective motor reactions
Trade offs between stimulus avoidance and other motivational requirements
Having opioid receptors
Reduction of responses by local anaesthetics and analgesics
High cognitive abilities
Showing avoidance learning
What evolution can make it even more harder to identify pain in animals?
Some have evolved to hide responses to pain
What behaviors may we see in response to acute pain?
- escape and avoidence
- volalistaion
- defensive behaviours
- direct attention towrads site of their pain
- might look normal but if you chnage hoe you are observing/ palpating you will see chnage
what behavioural respones might you see in chronic pain?
- protective or gaurding behaviours
- posture may be chnaged
- depression and learned helplessness
Decribe the physiological response to noxious stimulation
Results in stress responses - allow an animal to allocate bodily resources
Decribe the physiological response to activation of sympatho-adrenal catecholamine release
Changes in blood pressure, increased heart rate, changes in respiration, changes in muscle tone, defecation and urination
Decribe the physiological response to activation of hypothalamo-pituatary-adrenocortical axis
There is a glucocorticoid release
Why is there a problem with visual injury being a sign of pain?
- Injury can occur without pain
- Pain can occur without injury
- internal damage may be missed by human observation
Where else apart from relieveing pain are analgesics and anaesthetics used?
For pain assessment - like nerve blocks in horses
What are the problems with analgesic treatment?
- important that substances that prevent the animla from expressing pain rather than relieveing pain are not mistaken for analgesics
- analgesic drugs may have behavioural effects unreleated to pain and nociception
- drugs can also have nast side effects which is not good welfare practice
what methods of pain assesment are most likley to give the most accurate results?
Ones that combine objective and subjective elements
What are the two parts of the external ear?
- The Pinna which is the projection outside the skull
- External acoustic meatus (ear canal) connecting pinna to typanic membrane
Describe the shape of the pinna
Funnel shaped - wide distally to receive sound and narrows to connection with external acoustic meatus
What is the movility of the pinna?
It can oreintate towards sounds
What determines the pinna shape?
The articular cartilage which has different stiffeness so different shaped produced
what anchors pinna to skill so stays in place?
annular catilidge
where does skin and vessels adherev on external ear?
- skin adheres more firmly to concave surface (inner)
- vessels run on convex (outer) surface
where do the vessels which run on convex surface branch from?
caudal auricular artery
where does the external ear canal run from and too?
Runs from closure of auricular cartilidge to ear drum
What glands secrete wax?
sebaceous and tubular ceruminous glands
Describe the shape of the external ear canal?
curve ventrally then angle rostromedially
Is it true that sometimes you have to sedate to examine external canal with an otoscope?
Yes in cat and dog
Where is the middle ear found?
Within the tympanic cavity (bulla)
what is the tympanic bulla filled with?
gas
Descibe how the tympanic cavity is divided in the cat
- dorsal = epitympanic recess
- ventral - tympanic bulla
How does the tympanic membrane divide in ear?
Divides external acoustic meatus from the middle ear
where does the medial surface of the tympanic membrane attach?
To ossicles
What does the tympanic membrane attach to on temporal bone?
They tympanic ring of temporal bone
Laterally to medially name the aufitory ossicles
- Malleuse
- incus
- stapes
where does the handle of malleus attach too?
Eardrum
Is there an articulations at the level of the auditory ossicles?
Yes called malleus-incus-stapes
T/F the base of stapes inserts into vestibular window?
True
What are the two muscles that tense eardrim and ossicle chain?
- Tensor tympani
- Stepedius
what does sound cause to the middle ear?
- Vibration of the tympanic membrane
- Motion transmitted through ossiicle chain
- This causes vibration in the inner ear fluid at vestibular window
What connects tympanic cavity to nasopharynx?
The auditory tube
Describe the pathway of the auditory tube?
- openings in lateral wall of nasopharanx
- runs in cartilage trough
T/F is the auditory tube normall open?
False - usually collapsed
What does the opening of the auditory tube allow?
Equalisation of pressure on either side of the tympanic membrane and drainage of material ferom tympanic cavity
At the inner ear level what happens to sound?
Transformation of the sound into nerve impulses to be interperated by brain
What is the inner completely inclosed by?
Petrous temporal bone - osseous labyrinth
T/F there is a system of me,branous ducts and cavities in the inner ear?
True
What are the central cavities of the inner ear?
- utriculus
- sacculus
What are the ducts of the inner ear?
- 3 semicircular ducts from utriculus
- Spiral cochlear duct from sacculus
What ducts in inner ear are for balance?
The 3 semicircular ones from utriculus
what ducts in the inner ear are for hearing?
The spiral cochlear one from the sacculus
What stimulates sensory hair on receptor cells in wall of mebranous labyrinth?
Movement of endolymph
Within the utriculus and sacculus there are further receptors, name them and decribe their function?
Maculae - they have little crystals adhere to sensory hairs that determine position of the head relative to gravity triggering a response from said hairs
What angle are semicircular canals at?
Orientated at right angles
What is nystagmus?
“flicking” movement of eyes in response to movement of fluid in semicircular canals
What are the 3 parts of the osseous labryinth?
- central chamber
- semicircular canals
- cochlea
Describe the structure of the cochlea?
- It has spiral shape
- central osseous pyramid with canal running around and projecting spiral lamina
What three channals does the membrane from spiral lamina divide into?
- scala vestibuli
- cochlear duct
- scala tympani
Describe hearing at the inner ear
- vibration at vestibular window and cochlear window
- transmtted through perilymphatic space
- cause vibrations at basement membrane and movement of sensory cilia
- regestered by NT
- transmitted to vestibulocochlea nerve (8)
Name the 3 nerves that supply to ear?
- vestibulocochlear nerve
- facail nerve
- mandibular nerve
What does the ebstibulocochlear nerve divide into?
- Vestibular - balance
- Cochlear - hearing
Describe vascular supply to the external ear
- arterial supply from external carotid via caudal auricular
- venous drainage to maxillary vein
Describe the vascular supply to the middle and inner ear
- arterial supplu from occipital artery
What is an aural heamatoma?
Heamatoma in pinna under skin
Describe the 3 ways to image the ear?
- otoscope
- radiograph
- advanced imaginf - CT + MRI
If an animal dosent have a full orbit like a dog what is it called and what supports this?
Incomplete orbit and ligaments connect the two bits
T/F blindness can only come from the brain?
Flase - can be an obstruction to one of the structures of the eye which will restrict light getting in to form image
Name the three layers/Tunics of the eye from outer most to inner most
- fiberous tunic
- Vascular tunic
- neural tunic
What is the functions of the fiberous tunic?
- gives shape to eyeball
- protection to structures of the eye
What are the components and dunction of the vascular tunic?
- Blood vessels
- smooth muscle
- nutreint supply
- Control lens and pupil shape and size
What is the function of the neural tunic?
- Translation of visual signal into nerve impulses and transmission to brain - so light into ap
What are the two parts of the fiberous tunic?
- cornea and sclera
where do the cornea and sclera meet?
limbus
What can cause odema in cornea?
- build up of intersitual fluid in the CT of cornea and blocks vision
What is the main oart of the cornea?
Substania propria
what is substania propria inbetween?
The anteroir and prosteria lining epithelium
What is the anterior epithelium and what is it in continuation with?
- bowmans layer in continuation with conjunctival epithelium
What is the prosterior epithelium and what is it in continuation with?
The basement membrane in continuation with anteroir surface of iris
What is the sclera an entry point for?
for nerves and vessels
What attaches to the sclera?
Ocular muscles anteroir to the equator
What is the name of the thin membrane covering the cslera and what is its function?
- vagina bulbi
- Seperates eyeball from retrobulbar fat allowing eyeball free movement in socket
What does the vascular tunic consist of?
- Choroid
- Ciliary Body
- Iris
What are the functions of the vascular tunic?
- Vascular supply
- lens suspension
- control shape of lens and pupil
Where does the iris attach too?
Peripheral attachment to sclera and ciliary body
What is the central opening called in the iris?
Pupillllll
What controls the pupil size?
The smooth sphincter (parasympatetic) and Radial dilator (sympathetic) muscles
What does the iris divide?
Anteroir and prosterior chmabers of the eye
What are the Iridic Granules?
Projections from dorsal border across pupil seen in horses and ruminants
What is the ciliary body?
Thickened ridged ring around lens