Module 4 HW Questions Flashcards
Which pain can be precisely located?
fast pain
Which pain detects tissue destruction?
slow pain
Which pain is associated with prolonged suffering?
slow pain
Which pain is mostly cutaneous pain?
fast pain
Which pain begins 1 sec after stimulus?
slow pain
Which pain is sharp, stabbing, electric?
fast pain
Which pain is felt in deeper tissues?
slow pain
Which pain is where most 3rd order neurons terminate the reticular formation?
slow pain
Which pain can travel in type A delta fibers?
fast pain
Which pain secretes substance P?
slow pain
Which pain secretes glutamate?
both fast and slow pain
Which pain travels in the paleospinothalamic pathway?
slow pain
Which pain is where 1st order neurons synapse in the dorsal horn?
both fast and slow pain
Which pain synapses with 2nd order neurons in the ventral posterolateral nucleus of the thalamus?
fast pain
The ________ has more free nerve endings than deep tissue organs
skin
Bradykinin, potassium, proteolytic enzymes, and chemicals ___________ excite nociceptors
directly
Which hormone plays a role in increasing the sensitivity of nociceptors?
prostaglandins
Which chemicals are responsible for long suffering pain?
prostaglandins and substance P
Which chemical is most responsible for causing pain after tissue damage?
bradykinin
Intensity of pain felt is proportional to the local increase of _____________ in interstitial fluid
potassium
A person can pinpoint fast pain because fibers traveling in the neospinothalamic tract synapse at the same ___________ nucleus as the fasciculus gracilis of the dorsal medial lemniscus
VPL
What is the primary reason for tissue damage caused by tissue ischemia?
blocked blood flow
What chemical is responsible for pain caused by tissue ischemia?
lactic acid
What type of abnormal muscle condition excites both mechanosensitive nociceptors and chemical sensitive nociceptors?
muscle spasm
Where do most pain fibers traveling in the paleospinothalamic tract specifically terminate?
reticular nuclei
Which type of pain affects sleep, heart rate, and blood pressure?
slow pain
Which part of the CNS primarily perceives conscious pain?
brainstem
Which neuromodulator prolongs the opening of NMDA receptors?
substance P
What role does substance P play in long term potentiation of a pain pathway synapse?
facilitates/increases intracellular calcium
What abnormal pain sensation does long term potentiation cause?
hyperalgesia
Which hypothalamic nucleus is excited by pain signals?
paraventricular
Which neurotransmitter is released by neurons from the raphe nuclei?
serotonin
What is the role of serotonin in the analgesic system of the spinal cord?
excite enkephalin secreting neurons
Where are enkephalin neurons located?
dorsal horn at each cord level