Module 4 ch 1 Flashcards
Balance
Used to weigh ingredients. Class A electronic or torsion required for all compounding
Mortar and Pestle
Used to reduce particle size and or mix ingredients
Graduated cyclinder
Used to measure liquids by volume
Ointment paper
Used to prepare semi-solid dosage forms
Active Pharmaceutical Ingredient
The substance used in the compounding of a drug product that will display pharmacologic activity to treat, mitigate cure, prevent, or diagnose disease
Compounding facility
separate area within a pharmacy used for compounding
Geometric Dilution
Using equal amounts of ingredients during each step of compounding
Inactive ingredient (or excipient)
Substances required to compound a dosage from that are not intended to exert a pharmacologic effect
Levigate
to incorporate a solid into an ointment
Meniscus
The top of a liquid that is being measured
Concave in shape: measurement should be read at the bottom
Triturate
To reduce particle size by grinding in the mortar and pestle
Vehicle
a component for internal or external use that is used as a carrier or diluent in which liquids, semisolids, or solids are dissolved or suspended
Master formulation record
Created before compounding a preparation for the first time
Compounding record
Should be maintained a logged each time a compound is prepared
Simple
Appears in a peer-reviewed journal, or per manufacturer labeling that contains specific info on ingredients
Moderate
Making a preparation that requires special calculations or procedures to determine quantities of components
Complex
Making a preparation that requires special training, environment, facilities, equipment, and procedures
Solutions
-May require heating
-Combo of compatible solution or other ingredients that mix homogenously
Suspensions
solid substance is levigated in a mortar and pestle, wetted to form a paste, and transferred from the mortar
Emulsions
Mixtures of oil, water and an emulsifying agent that require special blending or homogenizing agent
Ointments
Incorporating other ingredients/dosage forms into a base. Commonly use a spatula on ointment paper/slab
Creams
Separating ingredients into “lipid” and “aqueous” categories, heating them separately above their melting points.
Gels
Involve incorporating a gelling agent, by either heating ingredients or altering their ph
Capsules
Can be prepared by hand or with special capsule-packing equipment
Tablets
Require packing/compressing equipment to prepare the molded dosage form
Suppositories
Can be made either by molding (incorporating ingredients into a melted base and pouring into a mold) or by hand rolling (ingredients incorporated into a semi-solid base, and hand-molded into a suppository shape).
