Modulators of Cardiac Contraction

Question 1

Modulator of Cardiac Contraction

• PDE 3 inhibitor–> increased calcium influx–> increases contraction
• Can be used along with B blockers because it works at a different receptor

Answer 1

Milrinone

Question 2

Modulator of Cardiac Contraction

• Calcium sensitizers
• Approved for congestive heart failure
  
  • Does not increase O2 demand, or promote arrhythmias

Answer 2

Pimobendan