Modification of Mendelian Ratio Flashcards
Most frequently encountered allele in a population, arbitrarily considered as normal.
Wild-type allele
Modification of genetic sequence.
Mutation
Mutation that brought about diminished functionality of the gene.
Loss of function mutation
Eventual loss of function of a gene due to mutation.
Null allele
Increased activity of a gene due to mutation.
Gain of function mutation
Mutation in a gene that does not necessarily altered its activity.
Neutral mutation
Lowercase and italicized (dd)
Recessive allele
Uppercase and italicized (DD)
Dominant allele
Both alleles are DOMINANT thereby expressing 2 distinct gene products.
Heterozygotes
In a population of organisms, the presence of three or more alleles of the same gene.
Multiple alleles
Simplest case of multiple alleles is that which three alternative alleles of one gene exist.
The ABO Blood Group
Discovered ABO Blood Group
Karl Landsteiner
A antigen
A phenotype
B antigen
B phenotype
A and B antigen
AB phenotype