Model Organisms Flashcards

1
Q

A non-human species that is extensively studied to understand basic biological phenomena, with the expectation that discoveries made in the model organism can be extrapolated to other species, including humans.

A

Model organism

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2
Q

Small adult size.

A

Model organism

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3
Q

Rapid development with short life cycles.

A

Model organism

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4
Q

Can be breed in large numbers.

A

Model organism

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5
Q

Readily available and inexpensive maintenance.

A

Model organism

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6
Q

Similar genes or similar-sized genomes to humans.

A

Model organism

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7
Q

Tractability to experimental methodology.

A

Model organism

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8
Q

8 types of Model Orgasim

A
  1. Bacteria
  2. Yeast
  3. Arabidopsis thaliana
  4. Caenorhabditid elegans
  5. Drosophila melanogaster
  6. Danio rerio
  7. Chick embryo
  8. Mouse
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9
Q

The foundations of molecular biology were based on studies of this model organism.

[model organism]

A

Bacteria

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10
Q

Antibiotics

[model organism]

A

Bacteria

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11
Q

Recombinant DNA technologies

[model organism]

A

Bacteria

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12
Q

Eukaryotic system

[model organism]

A

Yeast

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13
Q

Signaling molecules and cell cycle are nearly similar.

[model organism]

A

Yeast

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14
Q

Good model system to understand many human diseases including cancer.

[model organism]

A

Yeast

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15
Q

Ease of genetic manipulation allows its use for analyzing and functionally dissecting gene products from other eukaryotes.

[model organism]

A

Yeast

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16
Q

Last decade four Nobel prizes were awarded for discoveries involving yeast.

[model organism]

A

Yeast

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17
Q

One of the best characterized multicellular animal at the level of genomics, genetics, embryology.

[model organism]

A

Caenorhabditis elegans

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18
Q

Its genome is fully sequenced.

[model organism]

A

Caenorhabditis elegans

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19
Q

It is unique in that it can be grown and genetically manipulated with the speed and ease of a microorganism while offering the features of a real animal.

[model organism]

A

Caenorhabditis elegans

20
Q

Has a full set of organ systems, has complex sensory systems, shows coordinated behavior, and it is possible to trace the lineage of everyone of its approximately 1000 constituent cells.

[model organism]

A

Caenorhabditis elegans

21
Q

C. elegans Life Cycle and Research [4]

A
  1. Developmental and Cell
  2. Neurobiology
  3. Aging
  4. Human disease studies
22
Q

A versatile model organism that has been used extensively for biomedical research.

[model organism]

A

Fruit fly (Drosophila)

23
Q

Easy-to-manipulate genetic system and can be used to study development, physiology and behavior.

[model organism]

A

Fruit fly (Drosophila)

24
Q

Biological complexity comparable to that of a mammal.

[model organism]

A

Fruit fly (Drosophila)

25
Many organ systems in mammals have well conserved homologous in Drosophila. [model organism]
Fruit fly (Drosophila)
26
Has provided new insights into forms of cancer, neurodegenerative diseases, behavior, immunity, aging, multigenic inheritance, and development. [model organism]
Fruit fly (Drosophila)
27
Small size, short life cycle, ease of culture, and ability to readily produce mutations relevant to human health and disease. [model organism]
Danio rerio
28
The embryonic development can be seen through its transparent egg and closely resembles that of higher vertebrates. [model organism]
Danio rerio
29
Other shared features with humans include blood, kidney, and optical systems. [model organism]
Danio rerio
30
In addition, its genome is half the size of the mouse and human genomes, which is valuable in identification of key vertebrate genes. [model organism]
Danio rerio
31
Development in ex vivo. [model organism]
Danio rerio
32
Entire initial development is transparent. [model organism]
Danio rerio
33
48hrs is enough for the development of most of the organ systems. [model organism]
Danio rerio
34
The chick embryo provides an excellent model system for studying the development of higher vertebrates wherein growth accompanies morphogenesis. [model organism]
Chick embryo
35
Closest mammalian model organism to humans. [model organism]
Mus musculus (mouse)
36
Genes that code for proteins responsible for carrying out vital biological processes in both the human and the mouse share a high degree of similarity. [model organism]
Mus musculus (mouse)
37
A great system for studying and understanding human disease, as well as a mechanism for investigating new treatment strategies in ways that cannot be done in humans. [model organism]
Mus musculus (mouse)
38
Small flowering plant. [model organism]
Arabidopsis Thaliana (thale cress)
39
Has a small genome relative to other plants and is easily grown under laboratory conditions. [model organism]
Arabidopsis Thaliana (thale cress)
40
Amenable to some genetics particularly generation of transgenics. [model organism]
Arabidopsis thaliana (thale cress)
41
Allows insight into numerous features of plant biology, including those of significant value to agriculture, energy, environment, and human health. [model organism]
Arabidopsis thaliana (thale cress)
42
Colon cancer and other concerns.
E.coli
43
Cancer, Werner syndrome
S. cerevisiae
44
Disorders of the nervous system, cancer
D. melanogaster
45
Diabetes
C. elegans
46
Cardiovascular disease
D. rerio
47
Lesch-Nyhan disease, cystic fibrosis, fragile-X syndrome, and many other disease
M. musculus