Mod 2: Embryology Flashcards
Heart forms in week…
Heart begins to beat in week…
Forms and begins to beat in week 3
Neural tube forms/closes during weeks…
4-5
Heart can be detected via ultrasound … weeks after fertilization
5-6
What is the first organ to form?
the heart
Somatopleure
Splanchnopleure
Somatopleure: somatic mesoderm layer + adj ECTOderm
Splanchnopleure: splanchnic mesoderm layer + adj ENDOderm
Thin layer of what germ layer coats the yolk sac?
mesoderm
What 2 chemokines required to form cardiogenic crescent?
What is the resulting chemokine in the crescent?
BMP 2,4 (periph) and WNT inhibitors (cranial)
NKX-2.5 – beginning of heart tube
Do atria or ventricles fuse last?
atria fuse last (more atrial defects than ventricle defects)
Forelimbs form (b/f or after) hindlimbs Anterior seals up (b/f or after) posterior
Forelimbs b/f hind
Anterior b/f post
Atria begin…in fetal heart
caudal, inferior
What are the 2 parts of the bulbis cordis?
What do they form?
Conus cordis
Truncus arteriosus
**will form: ventricles, pulmonary trunk, aorta
Lung buds grow off of what tube?
gut tube
Lung associated structures that are endodermal in origin?
mesodermal in origin?
Endodermal: larynx, trachea, bronchi, lungs
Mesodermal: CT, cartilage, muscle
What are the first 2 stages of lung development?
Embryonic (26 days - 6 weeks)
- -resp diverticulum arises
- -3 rounds of branching, primordia of lungs, lung lobes, bronchopulmonary segments
- -stem of diverticulum forms trachea and larynx
Pseudoglandular (6-16 weeks)
- -resp tree undergoes more branching
- -formation of terminal bronchioles
When does embryonic heart flow begin?
3rd week