Mod 2: Embryology Flashcards

1
Q

Heart forms in week…

Heart begins to beat in week…

A

Forms and begins to beat in week 3

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2
Q

Neural tube forms/closes during weeks…

A

4-5

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3
Q

Heart can be detected via ultrasound … weeks after fertilization

A

5-6

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4
Q

What is the first organ to form?

A

the heart

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5
Q

Somatopleure

Splanchnopleure

A

Somatopleure: somatic mesoderm layer + adj ECTOderm
Splanchnopleure: splanchnic mesoderm layer + adj ENDOderm

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6
Q

Thin layer of what germ layer coats the yolk sac?

A

mesoderm

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7
Q

What 2 chemokines required to form cardiogenic crescent?

What is the resulting chemokine in the crescent?

A

BMP 2,4 (periph) and WNT inhibitors (cranial)

NKX-2.5 – beginning of heart tube

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8
Q

Do atria or ventricles fuse last?

A

atria fuse last (more atrial defects than ventricle defects)

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9
Q
Forelimbs form (b/f or after) hindlimbs
Anterior seals up (b/f or after) posterior
A

Forelimbs b/f hind

Anterior b/f post

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10
Q

Atria begin…in fetal heart

A

caudal, inferior

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11
Q

What are the 2 parts of the bulbis cordis?

What do they form?

A

Conus cordis
Truncus arteriosus
**will form: ventricles, pulmonary trunk, aorta

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12
Q

Lung buds grow off of what tube?

A

gut tube

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13
Q

Lung associated structures that are endodermal in origin?

mesodermal in origin?

A

Endodermal: larynx, trachea, bronchi, lungs
Mesodermal: CT, cartilage, muscle

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14
Q

What are the first 2 stages of lung development?

A

Embryonic (26 days - 6 weeks)

  • -resp diverticulum arises
  • -3 rounds of branching, primordia of lungs, lung lobes, bronchopulmonary segments
  • -stem of diverticulum forms trachea and larynx

Pseudoglandular (6-16 weeks)

  • -resp tree undergoes more branching
  • -formation of terminal bronchioles
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15
Q

When does embryonic heart flow begin?

A

3rd week

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16
Q

Where does gas exchange occur in embryo?

A

placenta

17
Q

Pharyngeal arches – each has what structures associated with it?

A

NAV, muscle, skeleton

18
Q

Aortic arches arise from

A

aortic sac (most distal part of truncus arteriosus)

19
Q

Aortic arch originates from

A

left dorsal aorta (pharyngeal arch 4)

20
Q

Ductus arteriosus connects…

What does it become in adult

A

Connects pulmonary trunk and aorta

Becomes ligamentum arteriosus in adult

21
Q

Aortic sac

A

place where pharyngeal arches branch from

22
Q

What abdominal organ has 2 parts that later fuse?

A

pancreas (dorsal and ventral pancreatic buds)

23
Q

Describe mesentery of foregut vs hindgut

A

Fore: dorsal and ventral mesenteries
Hind: dorsal mesentery only

24
Q

What week are intestines retracted back into abdomen?

A

week 11

25
Q

Amniotic cavity vs chorionic cavity size in weeks 2 vs 4

A

Week 2:
LARGE chorionic cavity
SMALL amniotic cavity

Week 4:
SMALL chorionic cavity
LARGE amniotic cavity

26
Q

Umbilical cord connects fetus to…

A

placenta