mnemonic Flashcards
Retroperiotneal organs
SAD PUCKER
S- Supra-renal (adrneal)
A- aorta + IVC
D- duadenum (2+3 parts)
P- pancreas (excp. tail)
U- ureters
C- colon (Ascd + dsc)
K-kidney
E-esophagus
R- rectum
M S 2 PROBLEMS are VAUGE
What are the organs create from the 1st pouch
all the organs start with M:
1. Muscle of mastication
2. meckl’s cartilage
3. meatus
4. middle ear
5. mastoid air cells
6. maxillary artery
7. mylohyoid
8. trigiMinal nerve (v3)
M S 2 PROBLEMS are VAUGE
What are the organs create from the 2st pouch
all the stuff start with S:
1. Stepedial artery
2. Seventh cranial nerve (smile)
3. Stapes
4. Staloid
5. Staylohyoid
6. Stapedius
M S 2 PROBLEMS are VAUGE
What are the organs create from the 3st pouch
all the organs start with P + problems
1. glossoPharyngeal nerve
2. stylo-Pharyngeal
3. Para-thyroid glands
4. Internal carotid + common carotid = Problem if severe
M S 2 PROBLEMS are VAUGE
What are the organs create from the 3st pouch
all the organs related to VAGUS nerve:
- Pulmonary artereis + ductus
- Right subclavian + Arch of aorta
- Superior laryngeal nerve
- Reccurent laryngeal nerve
- Thyroid cartilage
CLEAN the surface with SOAP
What are the dervities of Ectoderm»_space; Surface Ectoderm
C- canal (anal)
L- lens
E- epithlium
A- adenohypohysis
N- nipple
S-sweat glands
O-olfactory epithlium
A- auditory organs
P- parotid gland
a tube of NASPOREN
What are the dervities of Ectoderm»_space; Neural Tube
N-neural tube
A-astrocytes
S-spinal cord
P-pineal gland
O-oligodandrocytes
R-retina
E-epyndemeal cells
N-nuerohypoysis
SPAMS MOTEL w/crest toothpaste
What are the dervities of Ectoderm»_space; Neural crest
S-scwannomal cells
P-PNS
A-adrenal medulla
M-myetrtinc plexus
S- spiral membrane
M-melanocytes
O-odontoblast
T-thyroid C-cells
E- Endocardial cusshing
L- laryngeal cartilage
AG metabolic acidosis
MUDPILES
M- methanol
U-uremia
D-DKA
P-paraladhyde
I-iron
L- lactic acidosis
E- ethylene
S- salicylates (aspirin)
mnemonic
MEN 1
MEN 2a
MEN 2b
MEN 1- PPP
Pancreas
Pituatary
Para-thyorid
MEN2A- PPM
Para-Thyroid
Phecromocytoma
Medullary Thyroid carcinoma
MEN2B PMM
Pheochromocytoma
Medullary thyroid carcinoma
Marfan body hebitus
Song of Autosomal dominant
VON, VON ALS RB MEN
Tubrous, sphyros , huntington , Marfan Elhor Dan’s
NF 1 and 2 done be so FAP
Autosomal dominant, yes this song is clutch
Which medication induce P450?
CRAP GPS induce my range
C- Carbamazapine
R- rifampencin
A- alcohol (chronic use )
P-pehyntoin
G-griseofulvin
P-phenobarbital
S-sulfnylurea, St.jhon warts
medicaton»_space; subtype of Cyp450
Cyp- 1A2
AcetoAminophen
1 word , 2A= 1A2
medicaton»_space; subtype of Cyp450
2E1
Ethanol (alchohol)
you need to be 21 to drink Ethanol
2E1
medicaton»_space; subtype of Cyp450
2C9
Warfarin/ Comidin
inhibit factors: 2,7,9,10,C,S
2C9
medicaton»_space; subtype of Cyp450
2D6
Cardiovascular drugs
heart echo is D2 echo
therefore 2D6
Murmur type - sys or diastolic and pattern
AR, AS, MS, MR
“(h)ARD fall, ASS bump, MSD (missed) u, MRS thru”
ARD = Aortic Regurg, Diastolic; fall = decrescendo \
ASS = Aortic Stenosis, Systolic; bump = crescendo-decrescendo / \
MSD = Mitral Stenosis, Diastolic; u = decrescendo-crescendo _/
MRS = Mitral Regurg, Systolic; thru = holo-systolic —
What te different between BZD to barbituates on the influence on Chloride ion channels
BZD- increase frequency of Cl chennel opening
Barbiturates- Increase duration of Cl channel opening
Ben wants it happen more often (frequency)
but Barb wants it to last longer (duration)
What is the function of IL-1 to 6
HOT T-BONE stEAK
IL-1 = hot = fever
IL-2 = T -cells
IL-3 = BONE = BM
IL-4 = E = IgE
IL5 = A = IgA
IL6= K= aKute phase protein
What is the function of IL-7,8,10,12
IL-7 = lucky number = cells in BM are differeinting (like casino)
IL-8 =Chemotaxis»_space; neutrophil swimming in 8 shape
IL-10- anti-inflammatory
IL-12 - T0 to T1, Activate NK cells
Which cytokeins secreted by TH1 and TH2
TH1- IL-2,3 INF-y (for CD8)
Th2- IL-4,5,6
What causes the subtituation of Glutemic Acid to Valine in Hbs
Hysrophobic pocket»_space; ineraction among Hb moleculs»_space; polymerization and sickling
Which are the nephritic syndromes?
PSGN
RPGN
MPGN
all have P in there names
+
the 2 A’s = Alport syndrome and IgA nephropathy
HTN in pregnancy:
mnenonic?
HTN mom loves Nifedipind:
* Hydralazine
* Methyldopa
* Labetalol
* Nifedipine
Pt need NSAIDS but has gastric ulcers
Tx?
Celecoxib (cox-2 inhibitor - selective)
Pt on heparin w/induce Thrombocytopenia
what to do
stop heparin»_space; Direct thrombin inhibitor (Agetroban)
Pt need furosemide but has sulfa allergy
Ethancrynic acid (still loop diuretics)
What are the 2 HY drugs that ceause gnycomastia?
Spironolactone»_space; switch to eleprenone
Ketoconazole
Which Diuretics cause hypo and hyper calcemia?
Loop lose=
loop= hypocalcemia
Hyper- Thiazide
Which medication cause ototoxicity?
Aminoglycoside- Amin NO- N for nephrotoxoty, O- otoxicity
Loops
Cisplatin
ASA
Which medicaiton cause nephrotoxicity?
Aminoglycoside
amphotericin B
Which medication can cause Dilated cardiomyopathy and what the Tx
Doxorubicin / Danorubicin
Tx with Dexrazoxane
Which medication cause drug induce lupus and what Ab we will see
Anti Histone Ab
Hey,Im pretty much Quitting
Medications:
Hydralazine
Isoniazid
Procinamide
Methyldopa
Quinidine
What are the microcytic anemia?
TAILES:
- Talassemia
- Anemia of chronic disease
- Iron Def.
- Lead
- Sideroblastic anemia
Which pathogens can cause Endocarditis?
HACEK group:
Hemophilus spp.
Aggregatibacter
Cardiobacterium
Eikenella corodens
Kingella spp.
+
HAVE ABC
Ha-hacek
V-viridans (stre. epidyrmis)
E- enterococcus spp.
A-Aerus
B- strep.bovis (galacticus)
C- coxiella burneti
What is the Pathophysiology and gene in Stugr Weber syndrome
GNAQ mutation»_space; cappilary webs are unstable
**Weber = Web = capillary web **
Tuberous sclerosis
Genes, proteins, chromosome
TBS1»_space; chromosome 9»_space; Hemartin
TBS2»_space; Chromosome 16»_space; Tuberin
knock out = neoplasms
Tuberous = 8 letters.
8+1 = 9
8*2 = 16
Tuberous sclerosis tumors
Renal angiomyolipoma
Cardiac Rhabdomyoma
both have Myo = muscle = If you want to play the Tube you need a lot of muscle
NF1:
Gene, protein and patho, and presentation
Gene- NF1 (easy)
Chromosome: 17 (take 1 and the F )
Protein -TSG»_space; Neurofibromin (like the name of disease)
active RAS pathway.
Presentation:
I will have 1 coffe, this is Cute and de-LISCH- ous. Make me feel OPTIC-mistic
- Caffe ole
- Cutaneous fibromas
- Lisch nodulea (iris hemartomas)
- OPTIC gliomas
can cause also: Phochromocytoma, wilms tumor, axillary pigmentation
NF2:
Gene, protein
presenation, chromosome
Gene: NF2
Chromosome 22 (easy)
Protein- Merlin- which inhibit cell singaling
presenations:
Bi lateral things- like 2 = bi
Bi-lateral acoustic Swhannoma
CN V, VII, VIII
Bi leteral Juv. Cataract
NF II= Cerebe II opontine angle
Which Drug inhibit Squelene Epoxidase
Terbinafine
לזכור:
טורבינה כזאת כמו בעיבוד קמח בשוויץ עם צורת X שהיא קוראת בחוץ
Epxodiase
Which enzyme inhibit 14-a demathylase?
fungal pathway
Azoles family
The Azzholes prevent ergostholes
Which medications directy interfer with the Ergosterol membrane of the fungal
Amph B
Nystatin
Ampho-TEAR -icin a hole inthe plasma membrane
Which family of anti-fungal inhibit the cell wall formation and by which enzyme
Echinocadrin
Inhibit Beta glucan synthase for the cell wall.
E-KINDA- CAN-DO wall synthesis
all family member ends with Fungin (you will hit the wall if you have fun with gin (Fungin) )
Which anti-fungal inhibit DNA
Flucytosine
inhibit- 5 (Five) Uracil …. the name gives it mechanism
Flu like nuc (nucleus)
What is the MOA of Griseofluvine
Inhibit microtubule in fungal cells (inhibit mitosis, etc..)
Gris like Grass = Lets make some tubule of Grass
What is 3 importent side affect of Amp B
- Amphelabitis
- am-phph-ph-ph- teracin (fever and shaking from chills)
3.Am-FLOW-teracin - nephrotoxity (permeability and flow in the nephron)
What are the Rapid acting insulin and what is the peak time and duration?
Lispro
Aspart
Glulisive
remember: ** Rapid insulin do not LAG**
peak- 1-1.5
duration 3-4 hrs
What are the Short acting insulin and what is the peak time and duration?
Regular
Regular and Short
peak: 2.5
duraration: 4-6
What are the Intermediate insulin and what is the peak time and duration?
NPH
Remember: Intermediate is Not Particular Hastey
peak: 8 hrs
Duration : 10-16
What are the Long acting insulin and what is the peak time and duration?
Glargine
Determir
No peak
24h
God Damn 24h is a long time
For
RA
SA
intermediate
La
in insulin
wha is the peak and duration of each one:
RA- 1-1.5, 3-4 (strat from 1-1.5»_space; 1.5X2 = 3 -4)
SA- 2-2.5 (start from 2 (S like 2)»_space; 2.5X2 = 5 ~ 4-6
Intermediate - remember 8 ( peak) and double it for duration 16 (also 10)
LA- every day ends after 24h
Which diabetis medication
* inhibit gluconeogensis
* increase glycolysis
* increase peripheral glucose uptake
and what are its adverse effect?
METFORMIN
Adverse afect:
Lactic acidosis
B12 Def.
GI upset
METabolic acidosis (lactic)
Which Diabetic medication increse realse of insulin
what is the adverse affect?
and what the MOA
2 medications
Sulfanyl-Urea»_space; blocking the K chennels on beta cells in pancreas = de-polarization
Meglitidies - same is sulfnuyl just at a different binding site
adverse affect: Hypoglycemia for both
S.U- Disulfiram like reaction
Remember- all this medications ends with IDE
mega (meglitidies)- then you add LinIDE
Which DM family medication:
Glimepride
glipizide
glyburide
Sulfnyl urea
IDE take Sulfanyl urea
Which DM family is ending with Liptine?
what the MOA
and adverese effect
DDP-4 inhibitor
Lipton tea make you PP 4 more times
MOA: inhibit DDP4»_space; elevate levels of GLP-1
adverse: UTI, Respiratory infections
Which DM family is with Tide ends?
and what the adverse effect?
GLP-1 agonist
GLaoP Tide Tablets- האנשים המטומטמים שבעלו טבליות של מנקה כביסה
Adverse : Pancreatitis
Which DM medicaiton ends with Flozin
wha the MOA
what adverse effect
SGLT-2
MOA: inhibit NA-glucose co-transporter 2 in PCT
Adverse: Glucosiurea»_space; UTI, vaginal yeast infections
hyperkalemia
Dehydration
FlOZ INto the urine
Which DM family medication are these drugs:
Acarbose
Miglitol
what the MOA
and adverse effect
alpha- glucosidase inhibitor
MOA: prevent interstital brush border enzyme to break oligosaccharids into glucose.
adverse: GI upset, Gas, Bloating
A-CARB = inhibit carbs
Which calss medication end with Glitazone
what the MOA
what the adverse effect
Thiozolidinediones (longest name ever)
MOA: binds to PPAR-gamma nuclear factor »_space; increase insulin sensetivity
Adverse: HF + increase Fracture risk
Gliter zone in the PPAR-tyyyyy»_space; your heat is tired of dancing = HF and you can break a bone while dancing (increse risk fracture )
Hurler symptoms presenation
**HURLER*
H- hepatosplenomegaly
U- unuseal face features
R-ressecive (X-linekd)
L- (alpha) L-idudorindase def.
E- eyee clouded
R- retardation
S-short stubby fingers
remember: in hurler there is HER»_space; Alpha-L-IDurinidaSE = ALIDSE»_space; LADIES
death < 10 yrs
Chronic Giardiass can be cause by:
IgA def.
Giardiass»_space; GIA»_space; IgA
Which murmur have Opening snap after S2
Mitral stenosis
OS»_space; opening snap
Si2»_space; s2
Which AA is most abundace in Glycogen
Glycine »_space; Gly and Glycogen
superficial LN drainge:
Lesions in the medial foot will go trough which LN system
and Lateral lesions?
Medial- to superMedial nodes + Supralateral nodes»_space; Think also the M and also Super MAN = medial = supra LN
Lateral- popliteal and inguinal nodes»_space;Lateral to the popcical theres the inguinal node.
What does it mean when there’s a Ronchi? (on pulmonary examination)
Rhon Weezley = Wheezing
Rales in the Tails and Rhonci in the Bronchi
(rales = crackles)
Low fremitus vs high fremitus resons
Low fremitus- Lung with lots of air
High fremitus- lung with dense area (solid»_space; liquid»_space; air)
In atelectasis or pleural infusion, pneumothorax»_space; lung is insolated = diminish fremitus
AML mnemonic
A- Aure Rodes
M- myeloperoxidase +
L- leukemia
What are thr 5p of lichen planus
Pruritic
Purple/pink
Polygonal
papules
plaques
Aortic arch vascular derivative? 1-6
A- Ascending aorta
B- brachiocephalic (right)
C- Common carotid (left)
S- subclavian (left)
1st arch- Maxillary artery (1 = max)
2nd arch- Stapedial artery (Second = S)
3rd arch- Common carotid ( C= 3rd letter in ABC)
4th arch- aortic arch (left) + Right subclevian (right ) = pump to systemic body = 4 limbs for 4 arch
6 arch- pulmonary artery + ductus arteriosus
What is the muscarinic effect of Cholinergic toxicity?
DUMBLES
Diarrhea/diaporhesis
Urination
Miosis
Bronchospasm, Bradycardia
Emesis
Lacrimination
Salivation
Where the common carotid bifrocate?
C4:
BiFourcates at C4 (internal and external carotid)