GI

Question 1

Which factors secrete from the paretial cells

Answer 1

HCL-
Intrinsic Factor

Question 2

Which stimulate Paretial cells secretion

Answer 2

Stimulate- Vagus (Ach), Gastrin, Histamin

VGN makes Very Great HCL
Vagus
Gatrin
Histmine

Question 3

What the pprose of the intrinsic factor and from where it secreted?

Answer 3

Paretial cells in stomach Body.

Bind B12 and promote absorption in Terminal ilium

Question 4

Which type of anemia will occur in detruction of paretial cells in stomch and what will be the triad?

Answer 4

Pernicious anemia

1.Reversible dementia
2.Megaloblastic anemia- hypersegmented neutriphils, increase homocysteine and MMA
3.Subacute combine degeneration- dorsal colums , lateral corticospinal & spinocerebellar tract

Question 5

Which substacne secreted by Chief cells
and where they are located

Answer 5

Pepsinogen

which convert to pepsin in low PH (by the action of partieal cells&raquo_space; HCL)

Question 6

What substance secrete by G cells and where they are located

What stimulate it

Answer 6

location: Antrum

Secretion&raquo_space; Gastrin

Gastric Acid production, motility

Stimulate- Vagus, high PH, high stomach distention

Question 7

When I see somatostatin on the exam what sould I think of?

Answer 7

Inhibition= somtaotatin inhibit everything

Question 8

Which stomach cell secrete Histamine and where its located?

Answer 8

Entrochromaffin cells
and the body of the stomach

Question 9

Which Stimulate Histamine secretion and what is work?

Answer 9

Stimulate: Gastrin
Diffuse to paretial cells to release HCL

Question 10

Which stomach cells realse Ghrelin and what its function?

also what stimulate it

Answer 10

P/D1 cells
GHreliN= GH, Hunger, Nueropeptide Y
1. increase hunger- Lateral hypothalamus
2. increase Nueropeptide Y- Arcuate nucleus
3. increase GH - ant. pituatry

stimulate- Fasting and Sleep deprevation

Question 11

What type of cells secrete CCK (cholecyctokinin)
and what it is function?

Answer 11

I cells- in the duodoneum + Jejunum

functions: CCK
C- Contrast &raquo_space; contract the gallbladder
C- cuases&raquo_space; start the process of digestion in the deudonem (stimulate by AA, FA) secreation of digestive enzyme by the pancreas
K- kickoff

Question 12

Which cells produce somatostatin

Answer 12

D cells in the jejunum and pancrease

Question 13

Which cells will secrete Secretin and what is job?

Answer 13

S cells in the deudonum

1. increase bile secretion
2. increase pancreatic HCO3 secretion (w/o it pancreatic enzymes will not work)
3. Decrease Gastric acid secretion

Question 14

Which cells secrete GIP
(Gastric inhibitory polypeptide)
and what its job?

Answer 14

K-cells- in duodenum

1. increase insulin secretion
2. decrease gastric acid secretion
3. GIP= Get Insulin Popping

Question 15

What is the function of Parasympathetic ganglia in the intenstine?

Answer 15

Secrete Vasoactive inestinal peptide (VIP)- small intestine

1. increase water + Electrolycte secretion
2. Smooth muscle relaxation

excatly what vasoactive mean

Question 16

Which type of substence Mo cells in the small intestine secret?

and what he does?

Answer 16

Motilin
1. increase intestinal motility

Question 17

Which cells are realsing the following substacne?

Gastrin
Somatostatin
Cholyocstkinin
Secretin

Answer 17

G- gastrin (easy)
D- somatostatin (Dont! = inhibit)
I- chyloystkinin (2 i for I cells)
S- secretin (also easy)