Mixed 3a

Question 1

A tumor that shows a densely granulated somatotroph adenoma but the Gas subunit of G proteins in the tumor lack GTPase activity most likely have increased activity of

Answer 1

Adenylyl cyclase

Question 2

How is analgesics (morphine) to cause clinical deterioration after initiation of therapy

Answer 2

It is metabolized to active metabolites that accumulate

Question 3

When an object is swallowed whiles standing its most likely to get lodged in the

Answer 3

Lower right lung

Question 4

When the infraspinatus and teres minor muscle are being strengthen after an injury the arm should be

Answer 4

Lateral (external) rotation against resistance

Question 5

What is the cause of pale skin in a person with albinism (pale hair, blue eyes and unable to look at lights)

Answer 5

Inability to produce melanin

Question 6

A back pain that begins immediately after trying to lift weight of the ground to overhead is due to

Answer 6

Rupture of an intervertebral disc

Question 7

Cells from which part of the kidney are first to show signs of anoxic injury (nitrogen injury

Answer 7

Proximal Tubule

Question 8

A person experiencing DVT complains of shortness of breath and chest pain. The most appropriate immediate therapy should include a drug with what mechanism of action

Answer 8

Activation of antithrombin II

Question 9

What mechanism most likely underlies Li-Fraumeni syndrome

Answer 9

Impaired regulation of apoptosis

Question 10

What set of changes are likely to be observed in a patient exposed to smoking; mucus production and secretion, cilia activity, alveolar macrophages function

Answer 10

1. Mucus Production and
   secretions will be elevated
2. Activity of cilia and alveolar
   macrophages decreased

Question 11

Which extracellular matrix component is required to increase TENSIL strength after injury (postoperative abdominal incision)

Answer 11

Collagen

Question 12

The facial nerve exits through the

Answer 12

Rotundum

Question 13

Gram stain shows elliptical, PURPLE, BUDDING organism around catheter site. What is it?

Answer 13

Candida albicans

Question 14

In treating Rheumatoid arthritis when prednisone and methotrexate does not improve condition. The next step is to use a drug that blocks

Answer 14

Tumor necrosis factor-alpha

Question 15

In ventricular septal defect which population of cells were most likely absent during cardiac development

Answer 15

Ectodermal neural crest

Question 16

Progress difficult walking, weakness and decreased muscle bulk of lower extremities, patellar and achilles tendon reflexes are diminished. What is the likely cause

Answer 16

Degeneration of motoneurons of the lumbar cord

Question 17

Erection that is obtained only

through physical contact and does not last long is best explained as an intact spinal reflex between the

Answer 17

Sacral parasympathetic nerves and the pudendal nerves

Question 18

The difference in response to isoflurane only and isoflurane + nitrous oxide bing more potent is

Answer 18

Blood:gas partition coefficient

Question 19

A 1 week history of watery bloody diarrhea after a vacation from Kenya. Stool specimen shows trophozoites displaying erythrophagocytosis. Causal organism

Answer 19

Entamoeba histolytica

Question 20

Round worm larva in kids is most acquired through

Answer 20

Feces contaminated soil

Question 21

Dysmorphic features and numerous organ anomalies seen in a child of a mother that has experience many spontaneous abortions. The most likely cause of the abnormalities in this child is

Answer 21

Unbalanced chromosome rearrangement

Question 22

In herpes simplex virus the most appropriate drug inhibits which viral enzyme

Answer 22

DNA polymerase

Question 23

Intermittent anal itching in a pregnant woman, pain on defecation and occasional bright red blood with wiping. Examination shows a lesion what is the cause

Answer 23

Venous hypertension

Question 24

When the larynx is irritated by a particle of food and cough is provoked what is the position of the vocal crd through this sequence

Answer 24

1. While swallowing vocal 
 cord is closed
2. Immediately after irritation 
    its is still closed
3. While coughing vocal cord 
    is opened

Question 25

Thrombosis of the superior mesenteric artery will most directly cause ischemia of the

Answer 25

Jejunum