Miscellaneous Cultures Flashcards

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1
Q

General characteristics of spirochetes

A

Spiral microbes, 5-20 um in length.
Have a flexible cell wall & are motile.
Use several energy sources including carbs, amino acids, long chain fatty acids, or alcohols.
Gram neg

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2
Q

Leptospira family

A

Leptospiraceae

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3
Q

Borrelia and Treponema family

A

Spicochaetaceae

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4
Q

Treponema pallidum subsp. pallidumsyphilis mode of transmission

A

Direct sexual contact

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5
Q

T. pallidum subsp pertenue pathogenicity & mode of transmission

A

Yaws

Direct contact

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6
Q

T. carateum pathogenicity & mode of transmission

A

Pinta

Person to person contact

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7
Q

T. pallidum subsp. endimicum pathogenicity & mode of transmission

A
Endemic syphilis (Bejel)
Transmitted by direct contact
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8
Q

Primary phase of syphillus

A

10-90 days - primary lesion/chancre

Low sens for both treponemal & non-treponemal

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9
Q

Secondary phase of syphillus

A

2-12 weeks after primary lesion

High sens for both treponemal & non-treponemal

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10
Q

Tertiary phase of syphillus

A

No longer contagious unless recurrence of secondary phase

High sensitivity in treponemal tests

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11
Q

Nontreponemal tests

A

VDRL

RPR

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12
Q

VDRL

A

Venereal Disease Research Laboratory

Flocculation-cardiolipin antigen

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13
Q

RPR

A

Agglutination-bound cardiolipin with a carbon particle

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14
Q

Leptospira characteristics

A

Tightly coiled spirochete with hook on end

Aerobes (NG on artificial media)

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15
Q

Leptospira pathogenicity

A

Non specific influenza symptoms

Zoonotic disease from dogs, rat urine

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16
Q

Borrelia recurrentis pathogenicity

A

Relapsing fever - acute infection with fibrile episodes that can last for weeks

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17
Q

Borrelia burgdorferi Pathogenicity

A

Lymes disease

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18
Q

Leptospira vector

A

Dog, rodent urine

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19
Q

Borrelia recurrentis treatment

A

Tetracyclines

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20
Q

Endemic relapsing fever vector

A

Louse born

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21
Q

Epidemic relapsing fever vector

A

Tick born

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22
Q

Borrelia burgdorferi vector

A

Ixodes tick

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23
Q

Treatment for early Borrelia burgdorferi

A

Deoxycycline or amoxicillin

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24
Q

Treatment for late Borrelia burgdorferi

A

Ceftriaxone

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25
Q

Stage 1 of Lyme disease symptoms

A

Fever, headache, flu-like symptoms, ECM (erythema chromium migrans rash)

26
Q

Stage 2 of Lymes disease symptoms

A

Disseminated secondary skin lesions, migratory joint & bone pain, neurologic & cardiac pathology

27
Q

Stage 3 of Lymes disease symptoms

A

Joint, cardiac & neurological systems involved

28
Q

General characteristics of Chlamydia microbe

A

Known as obligate intracellular parasites
belongs to bacteria
Host cells are columnar or transitional epithelial cells

29
Q

C. trachomatis mode of transmission

A

Sexually transmitted

30
Q

C. trachomatis pathogenicity

A

Trachoma

Lymphogranuloma venereum

31
Q

C. trachomatis treatment

A

Sulfa drug sensitive

32
Q

C. psittaci mode of transmission

A

Transmitted from birds

33
Q

C. psittaci pathogenicity

A

Acute respiratory disease

34
Q

C. psittaci treatment

A

Usually sulfa resistant so another antibiotic is necessary

35
Q

C. pneumonia mode of transmission

A

Human transmission

36
Q

C. pneumonia pathogenicity

A

Acute respiratory pathogen
Otitis media
Effusion
Pneumoniae

37
Q

C. pneumonia treatment

A

Usually sulfa drug resistant

38
Q

Life cycle of Chlamydia

A

0 hrs: elementary body (infectious stage)
8 hrs: organize into reticulate bodies
24 hrs: reorganize into elementary bodies
30 hrs: multiplication stops
35-40 hrs: host cell dies, releasing EB’s

39
Q

General characteristics of Mycoplasmas

A

No cell wall, fastidious, facultative, need media with cholesterol & fatty acids for growth

40
Q

Mycoplasma hominis pathogenicity

A

Urogenital infections

41
Q

Mycoplasma hominis transmission

A

Sexual transmission

42
Q

Mycoplasma hominis treatment

A

Vancomycin

43
Q

Ureaplasma urealyticum pathogenicity

A

Urogenital infections

44
Q

Ureaplasma urealyticum transmission

A

Sexual transmission

45
Q

Ureaplasma urealyticum treatment

A

Erythromycin

46
Q

Mycoplasma pneumonia pathogenicity

A

Atypical pneumoniae

47
Q

Mycoplasma pneumonia transmission

A

Droplet transmission

48
Q

Mycoplasma pneumonia treatment

A

Erythromycin

49
Q

Rickettsiaceae genera

A

Rickettsia

Orienta

50
Q
Ehrlichia
Anaplasma
Cowdria
Wolbachia
Neorickettsia
A

Anaplasmataceae genera

51
Q

What causes rocky mountain spotted fever?

A

R. rickettsii

52
Q

What causes Boutonneause fever AKA Mediterranean spotted fever?

A

R. conorii

53
Q

What causes Rickettsial pox?

A

R. akari

54
Q

Diseases caused by R. prowagekii

A

Epidemic typus
Brill-Zinsser disease
Arthropod vector

55
Q

Diseases caused by R. typhi

A

Endemic (murine) typhus

Louse vector

56
Q

Cause of scrub typhus

A

Orientia tsutsugamushi

57
Q

Cause of trench fever

A

Bartonella quintana

58
Q

Cause of Q fever

A

Coxiella burnetii

59
Q

Characteristics of Erlichia spp

A

Obligate intracellular parasite

60
Q

Transmission of Erlichia spp

A

Arthropod borne, gram neg coccobacilli

Multiply in the phagosomes of host WBCs

61
Q

Clinical symptoms of Erlichia spp

A

Fever, leukopenic, anemia, thrombocytopenia

62
Q

Clinical ID of Erlichia spp

A

Inclusion in WBC