Miscellaneous Cultures Flashcards
General characteristics of spirochetes
Spiral microbes, 5-20 um in length.
Have a flexible cell wall & are motile.
Use several energy sources including carbs, amino acids, long chain fatty acids, or alcohols.
Gram neg
Leptospira family
Leptospiraceae
Borrelia and Treponema family
Spicochaetaceae
Treponema pallidum subsp. pallidumsyphilis mode of transmission
Direct sexual contact
T. pallidum subsp pertenue pathogenicity & mode of transmission
Yaws
Direct contact
T. carateum pathogenicity & mode of transmission
Pinta
Person to person contact
T. pallidum subsp. endimicum pathogenicity & mode of transmission
Endemic syphilis (Bejel) Transmitted by direct contact
Primary phase of syphillus
10-90 days - primary lesion/chancre
Low sens for both treponemal & non-treponemal
Secondary phase of syphillus
2-12 weeks after primary lesion
High sens for both treponemal & non-treponemal
Tertiary phase of syphillus
No longer contagious unless recurrence of secondary phase
High sensitivity in treponemal tests
Nontreponemal tests
VDRL
RPR
VDRL
Venereal Disease Research Laboratory
Flocculation-cardiolipin antigen
RPR
Agglutination-bound cardiolipin with a carbon particle
Leptospira characteristics
Tightly coiled spirochete with hook on end
Aerobes (NG on artificial media)
Leptospira pathogenicity
Non specific influenza symptoms
Zoonotic disease from dogs, rat urine
Borrelia recurrentis pathogenicity
Relapsing fever - acute infection with fibrile episodes that can last for weeks
Borrelia burgdorferi Pathogenicity
Lymes disease
Leptospira vector
Dog, rodent urine
Borrelia recurrentis treatment
Tetracyclines
Endemic relapsing fever vector
Louse born
Epidemic relapsing fever vector
Tick born
Borrelia burgdorferi vector
Ixodes tick
Treatment for early Borrelia burgdorferi
Deoxycycline or amoxicillin
Treatment for late Borrelia burgdorferi
Ceftriaxone