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Microbiology 484 > Miscellaneous Cultures > Flashcards

Miscellaneous Cultures Flashcards

1
Q

General characteristics of spirochetes

A

Spiral microbes, 5-20 um in length.
Have a flexible cell wall & are motile.
Use several energy sources including carbs, amino acids, long chain fatty acids, or alcohols.
Gram neg

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2
Q

Leptospira family

A

Leptospiraceae

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3
Q

Borrelia and Treponema family

A

Spicochaetaceae

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4
Q

Treponema pallidum subsp. pallidumsyphilis mode of transmission

A

Direct sexual contact

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5
Q

T. pallidum subsp pertenue pathogenicity & mode of transmission

A

Yaws

Direct contact

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6
Q

T. carateum pathogenicity & mode of transmission

A

Pinta

Person to person contact

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7
Q

T. pallidum subsp. endimicum pathogenicity & mode of transmission

A 
Endemic syphilis (Bejel)
Transmitted by direct contact
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8
Q

Primary phase of syphillus

A

10-90 days - primary lesion/chancre

Low sens for both treponemal & non-treponemal

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9
Q

Secondary phase of syphillus

A

2-12 weeks after primary lesion

High sens for both treponemal & non-treponemal

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10
Q

Tertiary phase of syphillus

A

No longer contagious unless recurrence of secondary phase

High sensitivity in treponemal tests

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11
Q

Nontreponemal tests

A

VDRL

RPR

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12
Q

VDRL

A

Venereal Disease Research Laboratory

Flocculation-cardiolipin antigen

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13
Q

RPR

A

Agglutination-bound cardiolipin with a carbon particle

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14
Q

Leptospira characteristics

A

Tightly coiled spirochete with hook on end

Aerobes (NG on artificial media)

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15
Q

Leptospira pathogenicity

A

Non specific influenza symptoms

Zoonotic disease from dogs, rat urine

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16
Q

Borrelia recurrentis pathogenicity

A

Relapsing fever - acute infection with fibrile episodes that can last for weeks

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17
Q

Borrelia burgdorferi Pathogenicity

A

Lymes disease

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18
Q

Leptospira vector

A

Dog, rodent urine

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19
Q

Borrelia recurrentis treatment

A

Tetracyclines

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20
Q

Endemic relapsing fever vector

A

Louse born

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21
Q

Epidemic relapsing fever vector

A

Tick born

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22
Q

Borrelia burgdorferi vector

A

Ixodes tick

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23
Q

Treatment for early Borrelia burgdorferi

A

Deoxycycline or amoxicillin

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24
Q

Treatment for late Borrelia burgdorferi

A

Ceftriaxone

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25
Stage 1 of Lyme disease symptoms
Fever, headache, flu-like symptoms, ECM (erythema chromium migrans rash)
26
Stage 2 of Lymes disease symptoms
Disseminated secondary skin lesions, migratory joint & bone pain, neurologic & cardiac pathology
27
Stage 3 of Lymes disease symptoms
Joint, cardiac & neurological systems involved
28
General characteristics of Chlamydia microbe
Known as obligate intracellular parasites belongs to bacteria Host cells are columnar or transitional epithelial cells
29
C. trachomatis mode of transmission
Sexually transmitted
30
C. trachomatis pathogenicity
Trachoma | Lymphogranuloma venereum
31
C. trachomatis treatment
Sulfa drug sensitive
32
C. psittaci mode of transmission
Transmitted from birds
33
C. psittaci pathogenicity
Acute respiratory disease
34
C. psittaci treatment
Usually sulfa resistant so another antibiotic is necessary
35
C. pneumonia mode of transmission
Human transmission
36
C. pneumonia pathogenicity
Acute respiratory pathogen Otitis media Effusion Pneumoniae
37
C. pneumonia treatment
Usually sulfa drug resistant
38
Life cycle of Chlamydia
0 hrs: elementary body (infectious stage) 8 hrs: organize into reticulate bodies 24 hrs: reorganize into elementary bodies 30 hrs: multiplication stops 35-40 hrs: host cell dies, releasing EB's
39
General characteristics of Mycoplasmas
No cell wall, fastidious, facultative, need media with cholesterol & fatty acids for growth
40
Mycoplasma hominis pathogenicity
Urogenital infections
41
Mycoplasma hominis transmission
Sexual transmission
42
Mycoplasma hominis treatment
Vancomycin
43
Ureaplasma urealyticum pathogenicity
Urogenital infections
44
Ureaplasma urealyticum transmission
Sexual transmission
45
Ureaplasma urealyticum treatment
Erythromycin
46
Mycoplasma pneumonia pathogenicity
Atypical pneumoniae
47
Mycoplasma pneumonia transmission
Droplet transmission
48
Mycoplasma pneumonia treatment
Erythromycin
49
Rickettsiaceae genera
Rickettsia | Orienta
50
``` Ehrlichia Anaplasma Cowdria Wolbachia Neorickettsia ```
Anaplasmataceae genera
51
What causes rocky mountain spotted fever?
R. rickettsii
52
What causes Boutonneause fever AKA Mediterranean spotted fever?
R. conorii
53
What causes Rickettsial pox?
R. akari
54
Diseases caused by R. prowagekii
Epidemic typus Brill-Zinsser disease Arthropod vector
55
Diseases caused by R. typhi
Endemic (murine) typhus | Louse vector
56
Cause of scrub typhus
Orientia tsutsugamushi
57
Cause of trench fever
Bartonella quintana
58
Cause of Q fever
Coxiella burnetii
59
Characteristics of Erlichia spp
Obligate intracellular parasite
60
Transmission of Erlichia spp
Arthropod borne, gram neg coccobacilli | Multiply in the phagosomes of host WBCs
61
Clinical symptoms of Erlichia spp
Fever, leukopenic, anemia, thrombocytopenia
62
Clinical ID of Erlichia spp
Inclusion in WBC

Microbiology 484 (15 decks)

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