Mieloma Multiple Sesion Flashcards

1
Q

Tipo de lesion patognomonica en ueso

A

Lesion en sacabocado

Osteoliticas

  • craneo
  • costilla
  • vertebras
  • Pelvis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Mortalidad en mieloma multiple

A

Infecciones
- Germenes encapsulados

Neumonia
Pielonfritis

St peunumoniae
Klebsiela

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Causa mas frecuente de falla renal

A

Excresion de cadenas ligeras

Proteinuria de Bence Jones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Tx de plasmocitoma unico

A

RT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Clinica caracteristica

A

Dolor oseo 70%
Sx anémico 30%
Perdida peso 25%
Infeccion 10%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Gold standard Dx

A

Electroforesis de Proteinas sericas

Banda densa (pico monoclonal) componente M

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Tipo de componente monoclonal mas frecuente de mieloma multiple

A

IgG 50%

IgA 20% (se asocia a falla renal)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Criterios de Kyle

A

> 10% de cel plasmaticas

Componente M en suero
IgG >3g/dl. IgA >2g/dl

Cadenas ligeras en orina > 1g/24hrs
Lesiones osteolíticas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Alteracion precursora de mieloma multiple o macroglobulinemia de walstrong

A

Gammapatia monoclonal de significado incierto

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tratamiento de elecciòn mieloma multiple en <65a

A

Transplante MO autologo
O
Transplante en Tandem (3 transplantes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Tx mieloma multiple con >65a

A

Mefalan + prednisona

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Tratamiento de Mieloma multiple asintomático

A

Ninguno

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Traslocación de muy mal pronostoci

A

T (14:14)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Clasificacion de Durie-salmon

Carolina Herrera tiene mieloma….

A

Calcio
Creatinina
Componente M (paraprteina)
Cadenas Ligeras en Orina

Hemogobina
Huesos (rx)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Gold standard de dx de Waldesnstrom

A

Electroforesis de proteinas con pico monoclonal IgM

Tiene adenopatías

How well did you know this?
1
Not at all
2
3
4
5
Perfectly