Midterms | Integumentary System Flashcards
Compositions of the integumentary system
Skin
Hair
Oil and sweat glands
Nails
Sensory receptors
Medical specialty that deals with the structure, function and disorders of the integumentary system
Dermatology
Dermatology is a medical specialty that deals with the (1), (2) and (3) of the integumentary system
- structure
- function
- disorders
Functions of the integumentary system
- Regulates body temperature
- Stores blood
- Protects body from external environment
- Detects cutaneous sensations
- Excretes and absorbs substances
- Synthesizes VITAMIN D
Other term for the skin
Cutaneous membrane
Largest organ of body in weight
Skin
Measurement, weight, and percentage of the skin in adults
Skin covers 2 square meters and weighs 4.5-5 kg (7% of the total body weight)
Thickness of the skin in diff body parts
0.5 mm (eyelids)
4 mm (heels)
1-2 mm (most of the body)
Superficial parts of the skin
Epidermis
Dermis
Storage depot for fat and contains blood vessels that supply the skin
Subcutaneous
What tissues does the hypodermis contain?
consists of areolar and adipose tissue
What type of epithelial tissue is the epidermis made up of?
Made up of keratinized stratified squamous epithelium
4 principal types of cells of the epidermis
- Keratinocytes
- Melanocytes
- Intraedpidermal Macrophanges/ Langerhans Cells
- Tactile Epithelial Cells/ Merkel Disc
Functions of each cells of the epidermis
- Keratinocytes: produces keratin
- Melanocytes: produces melanin
- Intraedpidermal Macrophanges/ Langerhans Cells: participate in immune response, help other cells of the immune system recognize an invading microbe and destroy it
- Tactile Epithelial Cells/ Merkel Disc: detect touch sensations
Helps protect the skin and underlying tissue from abrasion, heat, microbes, and chemicals
Keratin
What does keratin protect the skin and underlying tissue from?
Abrasion
Heat
Microbes
Chemicals
Function of melanin
Contributes to skin color and absorbs damaging UV light
Color range which the melanin contribute
Yellowish - red
Black - brown
One responsible for producing vitamin D
Skin
Advantage of vitamin D
Helps maintain protective barrier against sun damage
Nerve endings sensitive to pressure
Lamellated corpuscles
Where do intraepidermal macrophanges arise from?
Red bone marrow
Where is the tactile epithelial cell located?
Deepest layer of the epidermis (Stratum basale; along with melanocytes)
Principal layers/ strata of cells
- Stratum Basale
- Stratum Spinosum
- Stratum Granulosum
- Stratum Lucidum
- Stratum Corneum
Describe stratum basale
▪ Deepest layer
▪ Single row of cuboidal or columnar keratinocytes
▪ Contains KERATIN INTERMEDIATE FILAMENTS
Other term for stratum basale
Stratum germinativum
Protects deeper layer from injury
Keratin
Where is keratin attached to (in diff parts of the skin)
- Desmosomes (Stratum spinosum)
- Hemidesmosomes (Epidermis and Dermis)
Describe stratum spinosum
▪ Superficial to stratum basale
▪ With coarse bundles of keratin in intermediate filaments
▪ Cells shrink and pull apart appearing like thornlike spines
Function of thornlike spines of stratum spinosum
Provides strength and flexibility of skin
Describe stratum granulosum
▪ Middle of epidermis
▪ With 3-5 layers of keratinocytes undergoing APOPTOSIS
Assembles keratin intermediate filaments to keratin
Keratohyalin
Fuses plasma membrane and release lipid-rich secretion
Lamellar granules
Water-repellent sealant
Lipid-rich secretion
Function of lipid-rich secretion released by lamellar granules
Manage entry and exit of water and foreign substances
Describe stratum lucidum
▪ Present only in the thick skin (fingertips, palms and soles
▪ 4-5 layers of flattened, clear and dead keratinocytes (with thick plasma membranes)
Provides an additional level of toughness in this region of the skin
Stratum lucidum (Needs tp be thick for it is prone to friction)
Describe stratum corneum
▪ Cells are extremely thick, flat, plasma membrane-enclosed packages of keratin
▪ Final product of the process of keratinocytes
▪ Cells overlap one another like the scales on the skin of a snake
Constant exposure of skin to friction (increased cell and keratin production)
Callus
Abnormal thickening of stratum corneum
Callus
Describe the dermis
● Composition: Dense irregular connective tissue containing collagen and elastic fibers
● Has the ability to stretch and recoil easily
● Blood vessels, nerves, glands and hair follicle
Regions of the dermis
- Papillary region (superficial region)
- Reticular region (deeper region)
Small, nipple-shaped structures that project into the undersurface of the epidermis (with capillary loops/blood
vessels)
Dermal Papillae
Nerve endings sensitive to touch (warmth, coolness, pain, tickling and itching)
Corpuscles Of Touch/ Meissner Corpuscles
Contains bundles of thick collagen fibers, scattered fibroblasts and various wandering cells
Reticular region
What does the reticular region contain?
Bundles of thick collagen fibers,
scattered fibroblasts, and
various wandering cells
Arranged in a netlike manner (helps the skin resist stretching)
Collagen fibers
Arrangement of collagen fibers, and why?
Netlike manner. Helps the skin resist stretching
Provides strength, extensibility, ability to stretch, and elasticity
Collagen fibers and elastic fibers
Ability of substances to stretch and go back to its original shape
Elasticity
Dead, keratinized epidermal cells
Hair
Other term for hair
Pili
Anatomy of the hair
A. Shaft
B. Root
Describe the shaft of the hair
- Superficial portion
- Projects above the skin
Describe the root of the hair
- Hair deep to the shaft
- Penetrates dermis, sometimes the subcutaneous layer
3 concentric layers of the hair root
- Inner medulla
- Middle cortex
- Cuticle of the hair