Microbiology Review Q's Flashcards by Survive Medical School

Which of the following causes oral sores?

a. Coxsackievirus A
b. Coxsackievirus B
c. Hepatitis B
d. Ross river virus

a. Coxsackievirus A

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Which of the following may cause muscle and joint weakness?

a. Ross river virus
b. HIV
c. Parvovirus
d. Rubella

b. HIV

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Which of the following is treated with oseltamivir?

a. Hepatitis B
b. Ross river virus
c. Influenza virus
d. Rubella

g. Influenza virus

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Which of the following causes sharp chest and upper abdomen pain?

a. influenza virus
b. HIV
c. Coxsackievirus B
d. Hepatitis B

c. Coxsackievirus B

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Which of the following causes elevated liver enzymes, arthritis, & a rash?

a. influenza virus
b. HIV
c. Parvovirus
d. Ross river virus

d. Ross river virus

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Which of the following causes jaundice, muscle, and joint pain?

a. Coxsackievirus A
b. Coxsackievirus B
c. Hepatitis B
d. Ross river virus

c. Hepatitis B

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Which of the following causes generalized maculopapular rash and arthritis?

a. Parvovirus
b. Ross river virus
c. Influenza virus
d. Rubella

d. Rubella

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Which of the following causes a lacy rash, arthritis, and pure red cell aplasia?

a. influenza virus
b. Rubella
c. Parvovirus
d. Ross river virus

c. Parvovirus

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Which of the following causes myalgia?

a. Hepatitis B
b. Ross river virus
c. Influenza virus
d. Rubella

c. Influenza virus

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A pregnant women has joint pain. After delivey, doctors noticed malformations in the baby. Which of the following can cause this?

a. Hepatitis B
b. Ross river virus
c. Influenza virus
d. Rubella

d. Rubella

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Which of the following is more at risk of damage caused by pressure?

a. epiphysis
b. metaphysis
c. diaphysis

a. epiphysis

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Patient has osteomyelitis for 4 weeks, what’s a better description?

a. acute osteomyelitis
b. chronic osteomyelitis

b. chronic osteomyelitis

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How does a foreign material cause more osteomyelitis?

a. it inhibits the immune system
b. its a site for multiplication
c. the body attacks it

b. its a site for multiplication

nidus for infection

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Which of the following most commonly causes osteomyelitis?

a. oblique fracture
b. transverse fracture
c. hairline fracture
d. open fracture

d. open fracture

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In which of the following is osteomyelitis more recognizable?

a. children
b. teens
c. adults
d. elderly

a. children

systemic upset

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Which of the following species cause osteomyelitis in intravenous drug users?

a. S. aureus
b. Pseudomonas
c. H. influenzae
d. B. melitensis

b. pseudomonas

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Which of the following is least likely to get spinal osteomyelitis?

a. children
b. teens
c. adults
d. elderly

a. children

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Which of the following patients are we most likely has radiological evidence?

a. children
b. teens
c. elderly

c. elderly

they’re more likely to have chronic, and we’d see the sequestrum

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Which of the following is known to cause chronic osteomyelitis?

a. S. pyogenes
b. Bacteroides spp.
c. H. influenzae
d. C. perfringens

b. Bacteroides spp.

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Which of the following is most often isolated in all types of osteomyelitis?

a. S. aureus
b. C. perfringens
c. H. influenzae
d. M. tuberculosis

a. S. aureus

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Which of the following is known to cause chronic osteomyelitis?

a. S. pneumoniae
b. C. perfringens
c. Salmonella enterica
d. M. tuberculosis

d. M. tuberculosis

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Which of the following is known to cause osteomyelitis in patients with sickle cell?

a. S. pneumoniae
b. C. perfringens
c. Salmonella enterica
d. M. tuberculosis

c. Salmonella enterica

Salmonella spp.

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Which of the following is known to cause osteomyelitis in patients with diabetic foot lesions?

a. Anaerobic bacteria
b. Pseudomonas aeruginosa
c. S. pneumoniae
d. M. tuberculosis

a. Anaerobic bacteria

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Which of the following is known to cause osteomyelitis in nosocomial infections?

a. Anaerobic bacteria
b. Pseudomonas aeruginosa
c. S. pneumoniae
d. M. tuberculosis

b. Pseudomonas aeruginosa

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Which one means newly formed bone? a. involucrum b. sequestrum

a. involucrum

Which of the following is useless in the first week? a. MRI b. Ultrasound c. X-ray

c. X-ray

Which can be used for gram-negative? a. fusidic acid b. ciprofloxacin c. clindamycin d. teicoplanin e. vancomycin

b. ciprofloxacin

Which cannot be used alone? a. fusidic acid b. ciprofloxacin c. clindamycin d. teicoplanin e. rifampicin

e. rifampicin

Which is used for gram-positive? a. fusidic acid b. ciprofloxacin c. clindamycin d. teicoplanin e. rifampicin

d. teicoplanin

Which is able to penetrate the bone very well? a. fusidic acid b. ciprofloxacin c. clindamycin d. teicoplanin e. rifampicin

c. clindamycin

back pain is indicative of which? a. acute osteomyelitis b. chronic osteomyelitis

b. chronic osteomyelitis

Which usually affects a single long bone? a. acute osteomyelitis b. chronic osteomyelitis

a. acute osteomyelitis

Which causes osteomyelitis in a foreign body associated infection? a. Anaerobic bacteria b. Pseudomonas app. c. Propionibacterium app.

c. Propionibacterium app.

Which of the following causes spine inflammation and has the main symptom of low back pain? a. Spondyloarthritis b. Rheumatoid arthritis c. Ankylosing spondylitis

a. Spondyloarthritis | C= ankylosing means stiffness and that's the main symptom

Which HLA allele causes Ankylosing spondylitis? a. C33 b. B27 c. DR4 d. HC9

b. B27

Which TWO HLA alleles causes Rheumatoid arthritis? a. HLA-DR1 b. HLA-DR2 c. HLA-DR3 d. HLA-DR4

a. HLA-DR1 & d. HLA-DR4

Which TWO HLA alleles causes SLE? a. HLA-DR1 b. HLA-DR2 c. HLA-DR3 d. HLA-DR4

b. HLA-DR2 & c. HLA-DR3

Which HLA allele causes a more severe RA? a. HLA-DR1 b. HLA-DR4

a. HLA-DR1

Which hypersensitivity type is utilized in RA and SLE? a. Type I hypersensitivity b. Type II hypersensitivity c. Type III hypersensitivity d. Type IV hypersensitivity

c. Type III hypersensitivity

Which of the following so anti-CCP antibodies indicate? a. SLE b. RA c. malignancies

b. RA

Which is more common in RA? a. anti-IgA b. anti-IgD c. anti-IgM d. anti-IgG e. anti-IgE

d. anti-IgG

Anti-CCP antibodies are against which amino acid?

Citrulline

What's true about synovial lining? a. made of 4-5 layers of tissue b. intercellular fluid can't cross it c. made of fibroblasts and macrophages

c. made of fibroblasts and macrophages

What cytokine plays a major role in RA?

TNF-alpha (made by macrophages!)

Which of the following does the initial attraction of cells (macrophages & neutrophils) in RA? a. IL-1 b. TNFa c. IL-6 d. IL-7

a. IL-1

Which of the following activates T cells in RA? a. IL-1 b. TNFa c. IL-6 d. IL-7

c. IL-6

How does Methotrexate help RA patients?

Blocks lymphocyte cycling

Which leads to death in SLE patients? a. respiratory manifestations b. renal manifestations c. CNS manifestations d. skin manifestations

b. renal manifestations

Which is the least common manifestation in SLE patients? a. respiratory manifestations b. renal manifestations c. CNS manifestations d. skin manifestations

c. CNS manifestations

T/F: UV light only induces skin manifestations of SLE

F, it's a trigger for systemic and dermal manifestations

Which complement protein is used for SLE screening a. C1u b. C1q c. C1n d. C1p

b. C1q

Which of the following cytokines have a higher serum titer in people with active SLE? a. IL-7 b. IFN-a c. IFN-γ d. IL-9

c. IFN-γ

Non-specific polyclonal activation of B-cell occurs in a. SLE b. RA c. malignancies

a. SLE

Which TWO of the following cytokines are lower in people with SLE? a. IL-1 b. IL-2 c. IL-4 d. INF-g e. TGF- b

b. IL-2 & e. TGF- b

What mediates the clearance of immune complexes by phagocytic cells in the liver?

C receptors

What two complement proteins attract neutrophils?

C3a | C5b

Which hypersensitivity type is utilized to make auto-antibodies against RBC's in SLE? a. Type I hypersensitivity b. Type II hypersensitivity c. Type III hypersensitivity d. Type IV hypersensitivity

b. Type II hypersensitivity | Type II hypersensitivity leads to leukopenia, thrombocytopenia & hemolytic anemia

UV light induces apoptosis of which skin cells?

keratinocytes | Patient with SLE have an inappropriate expression of class II MHC molecules+ (Ro) Ag on them

What do drugs targeting BLyS proteins do?

stop the B-lymphocyte stimulator protein (BLyS) from activating B cells, thus reducing antibody production

Patient has fever and monoarticular joint pain. You suspect septic arthritis, what's your next course of action? a. aspirate joint b. give antimicrobial therapy

a. aspirate joint | mandatory to aspirate first

How do you treat arthritis in a prosthesis joint?

surgically remove the prosthesis (antimicrobial therapy won't work alone)

Patient with diabetic foot acquired septic arthritis, what's a likely causative organism? a. Coliforms b. Haemophilus influenzae (type b) c. Streptococcus agalactiae d. Salmonella

c. Streptococcus agalactiae

Which of the following needs both factor X&Y to grow? a. Coliforms b. Haemophilus influenzae (type b) c. Streptococcus agalactiae d. Salmonella

b. Haemophilus influenzae (type b)

Whats FLASE about disseminated gonococcal infections? a. Usually polyarticular b. Affects men and women equally c. Only 1-5% get articular manifestations

b. Affects men and women equally | women are asymptomatic, so the infection disseminates to the joints more often

10 year old has fever, diarrhea, jaundice, and joint swlling and pain. Whats more likely? a. Coliforms b. Haemophilus influenzae (type b) c. Streptococcus agalactiae d. Salmonella

d. Salmonella

An AIDS patient acquired septic arthritis, what's a likely causative organism? a. Coliforms b. Haemophilus influenzae (type b) c. Streptococcus agalactiae d. Salmonella

a. Coliforms | affect immunosupressed

Patient complains of sacroiliac joint pain. He visited his farm 3 days ago but didn't drink milk. Whats more likely? a. Brucella b. Salmonella c. Mycobacteria d. Streptococcus agalactiae

a. Brucella | don't have to drink raw milk to get it, its respiratory too

A one year old acquired septic arthritis, what's a likely causative organism? a. Coliforms b. Haemophilus influenzae (type b) c. Streptococcus agalactiae d. Salmonella

b. Haemophilus influenzae (type b)

Which organism stains black in SS agar? a. Coliforms b. Haemophilus influenzae (type b) c. Streptococcus agalactiae d. Salmonella

d. Salmonella

Patient had discharging sinus, which was drained, and knee pain. what's a likely causative organism? a. Brucella b. Salmonella c. Mycobacteria d. Streptococcus agalactiae

c. Mycobacteria (tuberculosis)

Which organism must be treated with triple therapy, debridement, and arthrodesis? a. Brucella b. Salmonella c. Mycobacteria d. Streptococcus agalactiae

c. Mycobacteria (tuberculosis) ``` (debridement= the removal of damaged tissue or foreign objects from a wound arthrodesis= artificial induction of joint ossification between two bones by surgery) ```

Microbiology Review Q's Flashcards

1. Viral Infections of Muscles, Joints, & Bones (1-10) -- 2. Infective Osteomyelitis (11-33) 3. Immunopathogenesis of Rheumatoid Arthriris (34-47) 2. Immunopathogenesis of Systemic Lupus Erythematosis (48-59)