Microbilogy Chapter 20 antimicrobial drugs

Question 1

Definition: Chemicals to cure.

Answer 1

Chemotherapy

Question 2

Act by killing or interfering with the growth of microbes within a host

Answer 2

Antimicrobial drugs

Question 3

A substance produceded by microbe that, in small amounts, inhibits another microbe

Answer 3

Antibiotic

Question 4

Kills the microbe and not affect the host.

Answer 4

Selective Toxicity

Question 5

Only kills 1 species.

Answer 5

Narrow spectrum

Question 6

Kills multiple types of microbes

Answer 6

Broad spectrum

Question 7

When antibiotic therapy kills normal flora. This can happen.

Answer 7

Superinfection

Question 8

The lack of resistance to antimicrobials

Answer 8

Bacterial susceptibility

Question 9

The ability to resist antimicrobial agents

Answer 9

Bacterial resistance

Question 10

Microorganisms present in or on host

Answer 10

Normal Flora

Question 11

Kill Bacteria

Answer 11

Bactericidal

Question 12

Inhibit growth of bacteria

Answer 12

Bacteriostatic

Question 13

Wanted to create “Magic Bullets”. Sularsan. Arsenaginic compound.

Answer 13

Paul Ehrlich

Question 14

Developed sulfa drugs. Sulfanilamide. Also discovered simisynthetic drugs and synthetic drugs.

Answer 14

Gerhard Domagk

Question 15

Why is it harder to kill gram negative microbes?

Answer 15

More complex cell wall.

Question 16

Have a B-lactum ring

Answer 16

Penicillin

Question 17

Treatment used for penicillin

Answer 17

• Oral

- Intramuscular

Question 18

Susceptibility to Penicillases also known as ________

Answer 18

B-Lactamase

Question 19

How do Penicillins work?

Answer 19

Attack bridges in the cell wall which destroys the cell.

Question 20

Blocks secretion of NAG and NAM from cytoplasm.

Answer 20

Bacitracin