Chapter 16 Flashcards

1
Q

Protein receptors located in the plasma membranes of defensive cells (phagocytes)

A

Toll-like receptors (TLR)

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2
Q

Substances that increase phagocytosis.

A

Opsonins

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3
Q

What is a complement?

A

Protein that get rid of microorganisms.

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4
Q

First line of defense against microorganisms

A
  • Skin (Sweat (lysozyme G+), dead cells, sebum)
  • Mucous membranes
  • Normal flora
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5
Q

Defense in the respiratory system.

A
  • Cilia
  • Mucous
  • Normal flora
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6
Q

Attaches to the cilia in the lungs and destroys them

A

B. pertussis (Whooping cough)

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7
Q

Second line of defense against microorganisms

A
  • Blood components
  • WBC’s
  • Phagocytes (Phagocytosis): neutrophils (arrive 1st), monocytes. (Phagocytosis: Ingestion and digestion of microorganism)
  • Plasma Proteins
  • Antibodies
  • Inflammation
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8
Q

3 types of formed elements?

A
  • Erythrocytes (RBC)
  • Platelets
  • Leukocytes (WBC)
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9
Q

First to arrive at site of infection. Perform phagocytosis.

A

Neutrophils

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10
Q

2 cell types that kill extraceularly?

A
  • Eosinophils

- Natural killer lymphocytes

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11
Q

Antimicrobial substances, against pathogens.

A

Nonspecific chemical defenses

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12
Q

How long does it take to make antibodies?

A

About 2 weeks

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13
Q

Defenses in digestive system

A
  • Low pH (Stomach acid)
  • Normal flora
  • Digestive enzymes
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14
Q

Monocytes that cross to the tissues

A

macrophages

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15
Q

Proteins that non specifically get rid of microorganisms.

A

complement

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16
Q

Complement activation results in:

A
  • Lysis
  • inflammation
  • Phagocytosis
17
Q

Antiviral proteins produced by animal cells after viral stimulation.

A

Interferons (IFN)

18
Q

A type of antimicrobial peptides (AMP) produced by neutrophils, macrophages.

19
Q

Phagocytosis

Name 3 phagocytes:

A
  • Neutrophils
  • Monocytes
  • Macrophages
  • Dendritic
20
Q

What types of defense mechanisms do the innate immune system use to combat extracellular pathogens?

A
  • Phagocytosis
  • Complement
  • WBC’s
21
Q

What types of defense mechanisms do the innate immune system use to combat intracellular pathogens?

A

-Interferons

22
Q

Combats worms in blood?

A

Eosinophils

23
Q

Results when chemicals called pyrogens trigger the hypothalamus to increase the body’s core temperature

24
Q

Anything that increases temperature.

25
Transfers iron.
Transferrins HINT: Trans-fe-rrins Fe=Iron
26
Non specific defense is
The body's defenses against any kind of pathogen
27
Neutrophils attach to vascular linings and move out of the cells in a process known as
Diapedesis
28
Margination is the process in which WBC......
Slow down, stop and attach to vessel walls
29
The primary phacoytes in the blood are
monocytes
30
Macrophages located in the liver are called
Kuffer cells
31
Fever is caused by chemicals known as
Pyrogens
32
Complement protein that acts as opsonin?
C3b
33
Phagocytes stick to the endothelium
Margination
34
Antiviral proteins produced by animal cells after viral stimulation
Interferons