Chapter 16 Flashcards

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1
Q

Protein receptors located in the plasma membranes of defensive cells (phagocytes)

A

Toll-like receptors (TLR)

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2
Q

Substances that increase phagocytosis.

A

Opsonins

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3
Q

What is a complement?

A

Protein that get rid of microorganisms.

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4
Q

First line of defense against microorganisms

A
  • Skin (Sweat (lysozyme G+), dead cells, sebum)
  • Mucous membranes
  • Normal flora
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5
Q

Defense in the respiratory system.

A
  • Cilia
  • Mucous
  • Normal flora
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6
Q

Attaches to the cilia in the lungs and destroys them

A

B. pertussis (Whooping cough)

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7
Q

Second line of defense against microorganisms

A
  • Blood components
  • WBC’s
  • Phagocytes (Phagocytosis): neutrophils (arrive 1st), monocytes. (Phagocytosis: Ingestion and digestion of microorganism)
  • Plasma Proteins
  • Antibodies
  • Inflammation
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8
Q

3 types of formed elements?

A
  • Erythrocytes (RBC)
  • Platelets
  • Leukocytes (WBC)
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9
Q

First to arrive at site of infection. Perform phagocytosis.

A

Neutrophils

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10
Q

2 cell types that kill extraceularly?

A
  • Eosinophils

- Natural killer lymphocytes

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11
Q

Antimicrobial substances, against pathogens.

A

Nonspecific chemical defenses

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12
Q

How long does it take to make antibodies?

A

About 2 weeks

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13
Q

Defenses in digestive system

A
  • Low pH (Stomach acid)
  • Normal flora
  • Digestive enzymes
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14
Q

Monocytes that cross to the tissues

A

macrophages

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15
Q

Proteins that non specifically get rid of microorganisms.

A

complement

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16
Q

Complement activation results in:

A
  • Lysis
  • inflammation
  • Phagocytosis
17
Q

Antiviral proteins produced by animal cells after viral stimulation.

A

Interferons (IFN)

18
Q

A type of antimicrobial peptides (AMP) produced by neutrophils, macrophages.

A

Defensins

19
Q

Phagocytosis

Name 3 phagocytes:

A
  • Neutrophils
  • Monocytes
  • Macrophages
  • Dendritic
20
Q

What types of defense mechanisms do the innate immune system use to combat extracellular pathogens?

A
  • Phagocytosis
  • Complement
  • WBC’s
21
Q

What types of defense mechanisms do the innate immune system use to combat intracellular pathogens?

A

-Interferons

22
Q

Combats worms in blood?

A

Eosinophils

23
Q

Results when chemicals called pyrogens trigger the hypothalamus to increase the body’s core temperature

A

Fever

24
Q

Anything that increases temperature.

A

Pyrogens

25
Q

Transfers iron.

A

Transferrins
HINT: Trans-fe-rrins
Fe=Iron

26
Q

Non specific defense is

A

The body’s defenses against any kind of pathogen

27
Q

Neutrophils attach to vascular linings and move out of the cells in a process known as

A

Diapedesis

28
Q

Margination is the process in which WBC……

A

Slow down, stop and attach to vessel walls

29
Q

The primary phacoytes in the blood are

A

monocytes

30
Q

Macrophages located in the liver are called

A

Kuffer cells

31
Q

Fever is caused by chemicals known as

A

Pyrogens

32
Q

Complement protein that acts as opsonin?

A

C3b

33
Q

Phagocytes stick to the endothelium

A

Margination

34
Q

Antiviral proteins produced by animal cells after viral stimulation

A

Interferons