methoxyflurane (ANALGESIC DRUG) Flashcards

1
Q

What are the pharmacokinetics for methoxyflurane

A

administration: inhaled
distribution: plasma protein
metabolism: lung cells
excretion: exhalation

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2
Q

What are the pharmacodynamics for methoxyflurane

A

methoxyflurane is an inhaled analgesic designed to be self-administered using a handheld device

can be used as a non-opioid alternative to morphine/ with morphine for very severe pain

believed to reduce pain signals across gap junctions

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3
Q

possible side effects of methoxyflurane

A

dizziness
coughing
drowsiness
headache
nausea
hypotension
bradycardia

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4
Q

how is methoxyflurane presented on the road

A

in a bottle of 3ml (inhaler)
vial of methocyflurane 99.9% inhalation vapour, liquid

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5
Q

how is methoxyflurane administered

A

through a handheld inhaler

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6
Q

what are the indications for methoxyflurane

A

relief of moderate to severe pain with trauma and associated pain

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7
Q

what are the contraindications for methoxyflurane

A

pt under 18y/o
recent use of methoxyflurane ( over 15ml in the previous week)
known hypersensitivity to methoxyflurane/anesthetic gases
pt with liver damage/impairment
chronic kidney disease (stage 4 or 5)
altered LOC due to head injury, drugs or alcohol
cardiovascular instability (like heart faliure, hypotension or arrythmia)
reduced rr
history of severe adverse reaction to inhaled anaesthetic gas or malignant hyperthermia

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8
Q

How long does inhaled methoxyflurane last for

A

25-35 mins

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9
Q

what is the dosage of methoxyflurane

A

1 bottle of 3ml inhaled
maximum of 2 bottles (6ml) inhaled in 24 hours

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10
Q
A
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