Adrenaline 1:10,000 (CARDIAC DRUG) Flashcards

What is the pharmacodynamics

1
Q

what are the pharmacokinetics for adrenaline 1:10000

A

administration: parental
distribution: plasma protein
metabolized: liver
excretion: urine

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2
Q

what are the indications for adrenaline 1:10,000

A

cardiac arrest
post rosc circulatory support

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3
Q

what are the contraindications for adrenaline 1:10,000 UPDATED

A

do not administer when patient’s core temp is below 30 degrees

if the temperature is between 30 and 35 degrees DOUBLE the time period between doses

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4
Q

what are the adverse effects of adrenaline 1:10,000

A

tachycardia
hypertension

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5
Q

what are the pharmacodynamics of adrenaline 1:10,000

A

adrenaline is a sympathomimetic that stimulates both alpha- and beta-adrenergic receptors.

Therefore myocardial and cerebral blood flow is enhanced during CPR and CPR becomes more effective due to increased peripheral resistance which improves perfusion pressures

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6
Q

what are the cautions of adrenaline 1:10,000 (UPDATED)- (who is at risk of hypertension)

A

severe hypertension which may occur in patients on non-cardio-selective beta blockers like propranolol

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7
Q

what is the dosage of adrenaline 1:10,000 during cardiac arrest (shockable rhythm)

A

shockable rhythm administer adrenaline after 3rd shock and after every other shock (5th,7th,9th etc)

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8
Q

what are the 2 routes of administering adrenaline 1:10,000

A

IV OR IO

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9
Q

what is the dose for adrenaline during cardiac arrest (non-shockable rhythm)

A

administer adrenaline IMMEDIATELY every 3-5 mins

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10
Q

what is the initial dosage for adrenaline 1:10,000 during cardiac arrest in an adult

A

1 milligram (mg) through rapid bolus

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11
Q

how is adrenaline 1:10,000 presented on the road

A

a pre-filled syringe containing 1milligram (mg) of adrenaline in 10 millilitres (ml)= 1:10,000 ADX

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12
Q

when and why do you give adrenaline 1:10,000 post ROSC

A

administer carefully within an adrenaline bolus

needed to maintain BP above 100mmHg

ensure this is flushed with 20ml of 0.9% saline

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13
Q

what is the initial dosage of adrenaline 1:10,000 in post ROSC for adults

A

initial dose= 50 microgram(mcg)

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14
Q

is there a max dose for adrenaline 1:10,000 during cardiac arrest and post ROSC in adults and children

A

no max dose limit

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15
Q

What is the repeat dosage for adrenaline 1:10,000 during cardiac arrest in adults

A

1 milligram (mg)

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16
Q

what is the repeat dosage for adrenaline 1:10,000 post ROSC in adults

A

50-100 microgram(mcg)

17
Q

what is the dose interval for adrenaline 1:10,000 during a cardiac arrest in adults and children

A

3-5mins