Metabolic Pathways: Gluconeogenesis Flashcards
1
Q
What is gluconeogenesis?
A
Formation of glucose from non carb precursors
2
Q
What are some non carb precursors used for glucose synthesis?
A
- Lactate
- Amino acids
- Glycerol
3
Q
Where does most of gluconeogenesi take place?
A
Liver
4
Q
The synthesis of _ in mitochondria is essential in gluconeogenesis
A
oxaloacetate - important for accepting acetyl groups from fat breakdown
5
Q
What is the chemical reaction of gluconeogenesis?
A
2 Pyruvate + 4ATP + 2GTP + H20 = Glucose + 4ADP + 2GDP
6
Q
Which precursor is used in the Cori cycle of gluconeogenesis?
A
Lactate
7
Q
Two hormones that regulate blood glucose level?
A
Glucagon and insulin
8
Q
When is glucogeneosis essential?
A
During periods of prolonged starvation
