Mendelian Inheritance Flashcards
What are the two diagrams that can show inheritance?
Pedigree diagram and punnet square.
What is sickle cell disease?
Single gene alteration of haemoglobin gene.
Who created Mendelian inheritance? And his(vegetable)
Mendel and his peas
What is an example of a recessive condition that is particularly common?
Cystic fibrosis
Thick and sticky mucus.
Infections that cause lung and pancreas problems.
Fertility and diabetic problems caused.
What is polymorphism?
Presence of genetic variation.
Doesn’t cause change in function.
What is achondroplasia?
Short limbed
Dominant allele
Autosomal dominant inheritance
Each child 50% chance
No ‘skipped generations
Equally transmitted by men and women
Male to male transmission
What did is Huntington’s disease?
a hereditary disease marked by degeneration of the brain cells and causing chorea and progressive dementia.
Dominant disease
1/2 chance
What is characteristic of duchenne muscular dystrophy?
X-linked condition
Unable to stand up properly
Boy cannot inherit from dad
If a boy has a father with a x-linked condition,…
The son cannot inherit the condition, he as to get Y chromosome from father.
CHARACTERISTIC OF X-LINKED
Only males affected classically
Can skip generations
Unaffected women and affect men transmit condition
No male to male transmission
