Mendelian inheritance Flashcards
What are the 3 laws of mendelian inheritance?
Law of segregation
Law of independent assortment
Law of dominance
What is the law of segregation?
During gamete formation, the alleles for each gene segregate from each other
So each gamete only carries one allele for each gene
What is the law of independent assortment?
Genes for different traits can segregate independently during the formation of gametes
What is the law of dominance?
Some alleles are dominant while some are recessive
An organism with at least one dominant allele will display the effect of the dominant allele
Disease X is caused by recessive allele ‘a’
An unaffected carrier father and non-carrier mother have children.
What is the risk of the children being a carrier and/or being affected?
No children will be affected
50% chance of child being unaffected carrier - Aa
50% chance of child being a non-carrier - AA
Disease Y is caused by recessive allele ‘q’
Both parents are un-affected carriers
What is the risk of their children being affected/carriers etc?
25% chance of affected child - qq
50% chance of unaffected carrier - Qq
25% of non-carrier - QQ
Disease E is caused by a dominant allele ‘t’
Both parents are heterozygous carriers.
What is the risk of their children being affected/carriers?
75% affected (25% homozygous, 50% heterozygous)
25% non carrier