memory pt 2 Flashcards
anterograde amnesia
inability to acquire new memories
- global anterograde amnesia, impairment in the ability to form new memories across a variety of areas
retrograde amnesia
inability to access old memories
may be incomplete
time dependant retrograde amnesia
commonly produced by traumatic brain injury
severity of injury determines how far back amnesia extends
system consolidation theory
hippocampus consolidates memories and holds then sends to be stored elsewhere
- accounts for preservation of old memories
- the more damage the more old memories lost
multiple trace theory
3 kinds of memory: autobiographic, factual semantic, general semantic
- each type dependant on diff brain area, old memories more resistant to amnesia b/c change location in brain as recalled
reconsolidation theory
memories rarely consist of single trace or neural substrate
each time memory used it is reconsolidated, reenters labile phase when recalled and stored as new memory
results in many different traces for same event
patient h.m
bilateral transection of temporal lobe for epilepsy management, left with anterograde amnesia
- could remember events before surgery
early hippocampal damage
inability to remember familiar surroundings or where object is located, appointments or events, daily activities
but can remember factual knowledge, how to read/write/speak
damage to neural connections to hippocampus
fimbria fornix: retro/anterograde amnesia
temporal lobe: contributes to amnesia
posterior neocortex and temporal lobe
four conclusions of hippocampus
anterograde deficits more sever than retrograde
episodic memories more affected than semantic
autobiographic memory severly affected
time travel is diminished
herpes simplex encephalitis
medial temporal lobe damage leads to anterograde amneisa
damage to insula contributes to retrograde amnesia
alzheimers
cellular change in medial temporal cortex and anterograde amnesia
damage to temporalassociation and frontal cortical areas related to retrograde amnesia
korsakoff syndrome
antero/retrograde amnesia, confabulation, meager content, lack of insight, apathy
- caused by thiamine deficiency resulting from alcohol
damage: medial thalamus, mammilary bodies of hypothalamus, frontal lobe atrohpy
psychogenic amnesia
infantile amnesia, sleep amnesia, dissociative states, multiple personality and simulated amnesia
asperger syndrome
autism in which individual has high intellectual function and excellent memory abilities