Membranes Flashcards
The cell’s cytoplasmic membrane is also known as the __ __
plasme membrane
Part (a) of the cell’s cytoplasmic membrane (plasma membrane) include:
- Separation of interior of cell to exterior of cell
Part (b) of the cell’s cytoplasmic membrane (plasma membrane) include:
- Interactions with other cells and exterior molecules
Part (c) of the cell’s cytoplasmic membrane (plasma membrane) include:
- Accumulation of cell nutrients; energy transduction; signal transduction
Part (d) of the cell’s cytoplasmic membrane (plasma membrane) include:
- Exclusion of toxic molecules and ions
Part (e) of the cell’s cytoplasmic membrane (plasma membrane) include:
- Cell locomotion; cell division
___ produced by amphipathic lipid molecules, such as fatty acids, interacting with water.
Monolayers
__ spherical lipid aggregates which have the long hydrophobic chains in the center and the charged carboxyl groups on the outside.
Micelles
__ produced spontaneously by lipids such as glycerophospholipids
Bilayers
___ naturally occurring spherical bilayer structures; can consist of multiple bilayers
vesicles
___ artificially prepared vesicles; used in laboratory experiments
liposomes
What are the two subunits of bilayers?
vesicles & liposomes
What is a subunit of monolayers?
micelles
___ are composed of hydrophobic and hydrophilic components
Micelles
Inside out micelles have the ___ on the outside
tails
Normal micelles have the ___ on the outside
heads
Monolayers are single layered with the ___ facing the air
tails
Bilayers have the __ facing the air
heads
The fluid mosaic model of membrane structure considers that the __ __ is a fluid supporting matrix for membrane proteins
lipid bilayer
Biological membranes are __ __, and both lipids and proteins are capable of __ within the bilayer
dynamic structures, movement
What are the two classes of membrane proteins?
Integral membrane proteins
Peripheral membrane proteins
What are integral membrane proteins also known as?
Intrinsic proteins
What are peripheral membrane proteins also known as?
Extrinsic proteins
Integral membrane proteins ____
extend into or through the lipid bilayer
Peripheral membrane proteins ___
external to the lipid bilayer
The ___ ___ is a fluid supporting matrix for membrane proteins
lipid bilayer
The ___ ___ of the bilayer is a barrier that separates one side of the membrane from another
hydrophobic interior
Membranes consist of a variety of ___
lipids, membrane proteins, and carbohydrates
Membranes are ___, ___ structures
complex, dynamic
What are the three groups of membrane?
- Lipids
- Proteins
- Carbohydrates
Glycerophospholipids, cholesterol, and other lipids are examples of ____
lipids
Integral (a-helix proteins & B-barrel proteins), peripheral are examples of ____
proteins
Glycoproteins and glycolipids are examples of ___
carbohydrates
Are a-helical proteins or B-barrel proteins more common?
a-helical proteins
Integral proteins go ___ the protein
through
Peripheral proteins do not go on the ___ of a protein
outside
Integral proteins are contained within the ___ ____.
lipid bilayer
Integral proteins are attached to the _____ by only a small ___ ____
membrane, hydrophobic segment
Integral proteins:
a) contained within the lipid bilayer
b) attached to the membrane by only a small hydrophobic segment
Peripheral proteins are loosely associated with the ___ of the membrane.
outside
Peripheral proteins __ to the membrane through __ ___ interactions with integral proteins
bind, non-covalent
What are examples of non-covalent interactions in peripheral proteins?
hydrophobic, ionic, hydrogen-bonding
Lipid-anchored proteins are ___ ____ (integral or peripheral)
membrane proteins
Lipid-anchored proteins are __ ___ to lipid molecules in the membrane
covalently linked
Lipid-anchored proteins include proteins bound to fatty acids such as __ __ and ___ ____
myristic acid and palmitic acid
What are two examples of integral membrane proteins?
a-helix protein
B-barrel protein
Carbohydrates in integral membrane proteins are ___ ___ for the MN blood group system
antigenic determinants
The ABO blood group system is due to ____ ____ to membrane sphingolipids (glycolipids).
carbohydrates attached
Blood group systems are due to ___ on the surface of red blood cells.
antigens
____ are typically the antigens on the surface of red blood cells. However, ___ can be antigens.
Carbohydrates, proteins
There are __ types of blood group systems
36
In ABO blood group system, carbohydrates are attached to the membrane _____
sphingolipids (glycolipids)
Some membranes proteins are anchored to ___ ___ by covalent attached to ___ that are inserted into the membrane lipid bilayer.
biological membranes, lipids