Genetic Code Flashcards
The genetic code connects the sequence of ___ ___ in a gene and its mRNA to the sequence of amino acids in a ____
nucleotide bases, protein
___ bases code for one amino acid
three
Code words that are three bases in length can specify __ amino acids
64
How many possible bases are there at each position?
4 possible bases (A,C,G or U)
The code words are ____
non-overlapping
The sequence is read continuously from a ___ starting point
fixed
The first base of the first code word must be identified. It can be located ____. AKA it might not be at the start
anywhere
Each amino acid can be coded by more than one __ __
code word
mRNA sequences have ___ possible reading frames
3
The precise identification of the translation start site is essential to have the reading frame with the correct ___ ___ sequence
amino acid
what are the 3 stop codons before the 3’ end?
UAA, UAG, UGA
what is the start codon from the 5’ end?
AUG
You can get up to __ code words per amino acid
6
what two amino acids are not coded by more than one sequence?
MET & TRP
How many code words does SER have?
6
___ out of the 64 amino acids specify amino acids
61
what two amino acids are not coded by more than one sequence?
MET, TRP
what codon is used the most in e coli?
CUG
what codon is used the least in e coli?
CUA
what codon is used the most in humans?
CUG
what codon is used the least in humans?
UUA
Code words for the same amino acid are not used equally, and large variations in the use of code words are found for ___ ___ and __ ____ ___
Human genes, E. Coli Genes
Each codon specifies only __ amino acid
one
Every amino acid is coded by more than one codon, expect for ___ and ___
Met and Trp
Codons for the same amino acid/chemically similar amino acids tend to have similar ____
sequences
Ex: all four codons with the sequence GGX, where X is U,C,A or G, code for glycine
The genetic code is almost universal: all living systems use the same __ ___
genetic code
Mitochondrial genomes show some differences; for example, UGA specifies ___ rather than stop
TRP