Meiosis And Recombination Flashcards
What is the goal of meiosis?
- make four haploid gamete that are not identical to the original
- when they combine you get a diploid
What is the goal of mitosis
-end up with two identical cells to the original that are both diploid
Interphase of meiosis
- Where cells spend a majority of their time
- where all the genetic material is replicated
Prophase I
- centrioles migrate to their poles
- homologous chromosomes pair up and form a tetrad
- crossing over
- longest step in meiosis
- nuclear envelope is disappearing
Metaphase I
-tetrads line up across metaphase plate
Anaphase I
- pulling apart homologous sets of chromosomes
- pulling apart tetrads
Telophase I and cytokenesis
Makes two haploid cells
Prophase II
- nuclear envelope disappears
- centromeres migrate to opposite poles
Metaphase II
Sister chromatids line up on metaphase plate
Anaphase II
Sister chromatids are pulled apart
Telephase II and cytokenesis
End up with four haploid gametes
What do we pull apart in meisis I? II?
I:Tetrads
II: sister chromatids
Problems in meiosis
- Nondisjunction
2. Translocation
Nondisjunction
- failure of tetrads to separate during meiosis i or sister chromatids in meiosis
- can lead to:
1. Down syndrome (trisomy 21)
2. Turner syndrome (x)
3. Kleinfelter syndrome (xxy)
Nondisjuction in meiosis I
Creates two trisomies and two monosomies