Dna Repair

Question 0

Types of dna repair

Answer 0

1. Proofreading
2. Nick translation
3. Mismatch repair
4. Base excision repair
5. Nucleotide-excision repair

Question 1

When is dna repair really important?

Answer 1

If you get a mutation

Question 2

Nick translation

Answer 2

• Can remove and kind of mixup in the dna backbone
• can be fixed right on the spot
• 5’-3’ exonuclease activity if dna pol I

Question 3

Mismatch repair

Answer 3

• parent strand is methylated to shows its the “good strand” and you only fix the daughter
• the wrong nucleotide is removed from the daughter strand along with whats around it
• dna pol III comes back and fills in the gap

Question 4

Proofreading

Answer 4

3’-5’ exonuclease can remove the last nucleotide if an error occurs

Question 5

Base excision repair

Answer 5

• a damaged base is removed leaving an AP site
• an AP endonuclease removes the rest of that nucleotide
• dna pol III fills in the gap

Question 6

Nucleotide-excision repair

Answer 6

• commonly used for UV light damage
• the damaged area is removed and surrounding area
• dna pol I fills in gap