Glycolysis Flashcards

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0
Q

Glucose -> ???

A

Glu(6c) -> 2pyr(3c)

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1
Q

Glucose catabolism reaction

A
  • glycolysis
  • C6H12O6 + 6O2 -> 6CO2 + 6H2O
  • oxidizes glucose
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2
Q

Anaerobicly

A
  • no oxygen

- gets its energy from glycolysis only

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3
Q

Yield per glucose

A
  • need 2ATP and make 4ATP YIELDS 2ATP
  • uses 2NAD and converts it to 2NADH. YIELDS 2NADH
    - must regenerate the NAD to continue
  • YIELDS 2 pyruvate
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4
Q

Oxidation and reduction in glycolysis

A
  • glucose is being oxidized to pyruvate

- nad is being reduced to nadh

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5
Q

Pyruvate —> ??

A
  1. Lactate
  2. Ethanol + CO2

** oxidizes nadh back to nad

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6
Q

Alcohol fermentation

A

Pyr -> acetaldehyde -> ethanol

  1. Decarboxylation
  2. Reduction
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7
Q

Cori cycle

A

Sending lactate to the liver to turn it back into glucose

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8
Q

Commitment step of glycolysis

A

F6p to f16bp by pfk1

-irreversible step

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9
Q

PFK1 activators

A
  1. Amp- means you dont have alot of ATP
  2. F6P- positive feedback
  3. insulin- released if you just ate alot of glucose. So chew up the glucose and make atp
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10
Q

PFK1 inhibitors

A
  1. ATP- negative feedback already have alot of energy
  2. F16BP- negative feedback
  3. Citrate- part of CAC so negative feedback
  4. Glucagon- released when you dont have alot of glucose in bloodstream. Means you havent eaten in a while so save the glucose for the brain
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11
Q

Energy investment steps

A
  1. g -> g6p

2. F6p -> f16bp

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12
Q

Energy payoff steps

A
  1. 13bpg -> 3pg (makes 2 atp)

2. Pep -> pyr (makes 2 atp)

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13
Q

What step is nadh made

A

Ga3p -> 13bpg

Nad->nadh (make 2 nadh)

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14
Q

Where does glycolysis take place

A

Cytosol

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