Glycolysis Flashcards
0
Q
Glucose -> ???
A
Glu(6c) -> 2pyr(3c)
1
Q
Glucose catabolism reaction
A
- glycolysis
- C6H12O6 + 6O2 -> 6CO2 + 6H2O
- oxidizes glucose
2
Q
Anaerobicly
A
- no oxygen
- gets its energy from glycolysis only
3
Q
Yield per glucose
A
- need 2ATP and make 4ATP YIELDS 2ATP
- uses 2NAD and converts it to 2NADH. YIELDS 2NADH
- must regenerate the NAD to continue - YIELDS 2 pyruvate
4
Q
Oxidation and reduction in glycolysis
A
- glucose is being oxidized to pyruvate
- nad is being reduced to nadh
5
Q
Pyruvate —> ??
A
- Lactate
- Ethanol + CO2
** oxidizes nadh back to nad
6
Q
Alcohol fermentation
A
Pyr -> acetaldehyde -> ethanol
- Decarboxylation
- Reduction
7
Q
Cori cycle
A
Sending lactate to the liver to turn it back into glucose
8
Q
Commitment step of glycolysis
A
F6p to f16bp by pfk1
-irreversible step
9
Q
PFK1 activators
A
- Amp- means you dont have alot of ATP
- F6P- positive feedback
- insulin- released if you just ate alot of glucose. So chew up the glucose and make atp
10
Q
PFK1 inhibitors
A
- ATP- negative feedback already have alot of energy
- F16BP- negative feedback
- Citrate- part of CAC so negative feedback
- Glucagon- released when you dont have alot of glucose in bloodstream. Means you havent eaten in a while so save the glucose for the brain
11
Q
Energy investment steps
A
- g -> g6p
2. F6p -> f16bp
12
Q
Energy payoff steps
A
- 13bpg -> 3pg (makes 2 atp)
2. Pep -> pyr (makes 2 atp)
13
Q
What step is nadh made
A
Ga3p -> 13bpg
Nad->nadh (make 2 nadh)
14
Q
Where does glycolysis take place
A
Cytosol