Mehl. TORCHeS: other - VZV, Parvovirus 19

Question 1

Parvo. cause what anemia?

Answer 1

Parvo B19 can cause aplastic anemia in utero or in the neonate, with increased risk in
sickle cell.

Question 2

Parvo. aplastic anemia definition?

Answer 2

all 3 hematologic cell lines are down (i.e., RBCs, WBCs, and platelets).

Question 3

Parvo. - Can sometimes cause a pure RBC aplasia (i.e., only RBCs down).

Answer 3

.

Question 4

Parvo.

The term “fetal hydrops” refers to heart failure in utero, and can suggest severe
anemia, such as with maternal Parvo infection. In other words, the stem can say the
mom had a flu-like illness or cold, followed by hydrops in the fetus à answer =

Answer 4

parvovirus 19

Question 5

Parvo.
Q can ask how to confirm Parvo infection in neonate if suspected -> answer = ?

Answer 5

Check Parvo IgM titers in neonate.

Question 6

VZV. can cause what CP?

Answer 6

cause microcephaly and limb hypoplasia.

Question 7

VZV. If mother contracts VZV for the first time between 5 days prior to parturition until 2
days after, prophylaxis?

Answer 7

Varicella immunoglobulin must be given to the neonate.

Question 8

VZV.
Kids with congenital VZV syndrome (as well as those who are immunocompromised),
are at increased risk of???

Answer 8

pediatric shingles (just know this Dx exists / “is a thing”).

Question 9

VZV.
If neonate is exposed to child with active varicella, if the mother of the neonate
previously had chickenpox or was vaccinated, prophylaxis?

Answer 9

you do not need to give VZV IVIG to the
neonate. This is because the neonate has passive immunity from the transplacental IgG.

Question 10

VZV. Should be noted that pregnant women who contract VZV can get what disease? weird

Answer 10

can get pneumonia from it
(sounds weird, but it’s a factoid you could be aware of).