UW table for prophylactic antiD-Ig admin. 02-14 (1)

Question 1

……
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
Ectopic pregnancy
Threatened abortion
Hydatidiform mole
CVS, amniocentesis
Abdominal trauma
2nd- and 3rd trimester bleeding
External cephalic version

Answer 1

At 28-32 weeks gestation

Question 2

At 28-32 weeks gestation
…..
<72h after spontaneous abortion
Ectopic pregnancy
Threatened abortion
Hydatidiform mole
CVS, amniocentesis
Abdominal trauma
2nd- and 3rd trimester bleeding
External cephalic version

Answer 2

<72h after delivery of Rh(D)-positive infant

Question 3

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
….
Ectopic pregnancy
Threatened abortion
Hydatidiform mole
CVS, amniocentesis
Abdominal trauma
2nd- and 3rd trimester bleeding
External cephalic version

Answer 3

<72h after spontaneous abortion

Question 4

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
…..
Threatened abortion
Hydatidiform mole
CVS, amniocentesis
Abdominal trauma
2nd- and 3rd trimester bleeding
External cephalic version

Answer 4

Ectopic pregnancy

Question 5

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
Ectopic pregnancy
…….
Hydatidiform mole
CVS, amniocentesis
Abdominal trauma
2nd- and 3rd trimester bleeding
External cephalic version

Answer 5

Threatened abortion

Question 6

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
Ectopic pregnancy
Threatened abortion
……
CVS, amniocentesis
Abdominal trauma
2nd- and 3rd trimester bleeding
External cephalic version

Answer 6

Hydatidiform mole

Question 7

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
Ectopic pregnancy
Threatened abortion
Hydatidiform mole
…..
Abdominal trauma
2nd- and 3rd trimester bleeding
External cephalic version

Answer 7

CVS, amniocentesis

Question 8

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
Ectopic pregnancy
Threatened abortion
Hydatidiform mole
CVS, amniocentesis
….
2nd- and 3rd trimester bleeding
External cephalic version.

Answer 8

Abdominal trauma

Question 9

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
Ectopic pregnancy
Threatened abortion
Hydatidiform mole
CVS, amniocentesis
Abdominal trauma
…….
External cephalic version

Answer 9

2nd- and 3rd trimester bleeding

Question 10

At 28-32 weeks gestation
<72h after delivery of Rh(D)-positive infant
<72h after spontaneous abortion
Ectopic pregnancy
Threatened abortion
Hydatidiform mole
CVS, amniocentesis
Abdominal trauma
2nd- and 3rd trimester bleeding
….

Answer 10

External cephalic version

Question 11

kai isijautrina, tai per antra nestuma gali IgG praeiti placenta –> hemolytic disease of the newborn (ie, hydrops fetalis).

Answer 11

Those women who are Rh(D)-negative and have a negative antibody screen (eg, negative Coombs test) –> give Rh(D)Ig

Question 12

UW case: ectopic pregnancy + rupture. best next step?

Answer 12

Give Anti-D immunoglobulin

wrong - no additional Tx

Question 13

UW case: 34age + 13 weeks + heavy bleeding. blood type AB negative. Next step?

Answer 13

give RhoDIg

Question 14

UW. Rh case. alloimunization incr. risk for what fetal condition?

Answer 14

hemolytic disease of the newborn (eg, hydrops fetalis) in subsequent pregnancies.

Question 15

Anti-D immunoglobulin is prophylactically administered at 28 weeks gestation because it persists for 12 weeks and protects against any potential exposure to fetal red blood cells through the third trimester.

Answer 15

It is given again within 72 hours of delivery if the baby is Rh D-positive.

Question 16

UW. 3 tests in first semester - hemato?

Answer 16

blood type,
Rh D status,
and the presence of any red blood cell antibodies (antibody screen or indirect Coombs test)

Question 17

UW. Coombs ie. antibodies may be positive in….???

Answer 17

In women who have formed antibodies from exposure to another’s blood (eg, blood transfusion, prior pregnancy).

Question 18

UW. Antibody screen is particularly important in an Rh D-negative multiparous woman to evaluate for anti-D antibodies that may have formed in response to a prior pregnancy with an Rh D-positive fetus.

Answer 18

.

Question 19

UW. in case was 2nd pregnancy. in first trimester A Rh negative, Coombs negative. now 28 weeks. best step in Mx?

Answer 19

Indirect coombs tests

Question 20

!!!!!! UW. in case was 2nd pregnancy. in first trimester A Rh negative, Coombs negative. now 28 weeks –>

only 10 proc. answered correctly

Answer 20

This woman’s negative antibody screen in the first trimester indicates that she is not alloimmunized.

However, prior to prophylactic administration of anti-D immunoglobulin, another antibody screen (ie, indirect Coombs test) is indicated to ensure that spontaneous alloimmunization has not occurred because anti-D immunoglobulin provides no benefit in previously sensitized patients.

In addition, identification of alloimmunization allows for appropriate management of complications (eg, hydrops fetalis).

Question 21

UW. Educational objective:
Rh(D)-negative pregnant patients not previously alloimmunized (eg, negative indirect Coombs test) require anti-D immunoglobulin to prevent Rh D alloimmunization.

!!!!!!!!!!!!Anti-D immunoglobulin is universally administered at 28 weeks gestation following a repeat negative antibody screen.

Answer 21

.