Mehl. abortion implementation + HRT 03-24 (1)

Question 1

M. Abortion. Plan B. What to do?

Answer 1

Emergency contraceptive meds.

Question 2

M. Abortion. Plan B. what drug (common)? within how many days?

Answer 2

Levonorgestrel (progesterone analogue); effective within 3 days.

Question 3

M. Abortion. Plan B. other drug than levono? within how many days?

Answer 3

Ulipristal (selective-progesterone receptor modulator; SPRM); effective within 5 days.

Question 4

M. Abortion. Plan B. non drug?

Answer 4

Once again, copper IUD can be used for emergency contraception and is most effective if inserted.

Question 5

M. Abortion. Plan B. most effective?

Answer 5

Copper IUD can be used for emergency contraception and is most effective if inserted.

Question 6

M. Abortion. Plan C. what principle?

Answer 6

Abortion meds.

Question 7

M. Abortion. Plan C. what drug regimen?

Answer 7

Mifepristone (progesterone receptor antagonist) is used up to 10 weeks post-intercourse. –>This is followed by misoprostol (PGE1 analogue) 1-2 days later.

Question 8

M. Abortion. Plan D. regimen?

Answer 8

Surgical abortion.

Question 9

M. Abortion. Plan D. What methods? 6-16 weeks

Answer 9

Vacuum aspiration can be done 6-16 weeks.

Question 10

M. Abortion. Plan D. What methods? >16 weeks

Answer 10

Dilation and evacuation (D&E) done >16 weeks.

Question 11

M. HRT. what drugs?

Answer 11

Estrogen combined with progesterone

Question 12

M. HRT. WHAT ONLY INDICATION?

Answer 12

Only approved for severe perimenopausal vasomotor symptoms (i.e., hot flashes, urge incontinence, atrophic vaginitis).

Question 13

M. HRT. Is bone density preservation is indication?

Answer 13

Not given to help preserve bone density or for positive role on mood and neurocognition, since incr. absolute estrogen exposure in women incr. risk of breast cancer, MI, and thromboembolic events (i.e., DVT, PE, stroke). The latter is because estrogen upregulates fibrinogen and factors V and VIII.

Question 14

M. HRT. risk for what? why?

Answer 14

Can cause unopposed estrogen and ­incr. endometrial cancer risk only if the woman inadvertently stops taking the progesterone component (i.e., endometrial hyperplasia -> incr. endometrial adenocarcinoma risk).

Question 15

M. HRT. Estrogen alone can considered only if the woman has Hx of what??

Answer 15

Hysterectomy (i.e., no ­ endometrial adenocarcinoma risk).

Question 16

M. HRT. what about libido?

Answer 16

Can cause decr. libido due to decr. endogenous androgen production (i.e., incr.­ negative-feedback at hypothalamus / anterior pituitary -> decr. GnRH -> decr. LH and FSH).