UW syphilis table (normal obstr failas) 02-13 (1)

Question 1

When screening?

Answer 1

universal for 1st trimester

Question 2

when screen in high risk patients?

Answer 2

in 3rd trimester and delivery

Question 3

Serologic tests type?

Answer 3

Nontreponemal (RPR=rapid plasma reagin; VDRL)
Treponemal (FTA-ABS = fluorescent treponemal antibody absorption)

Either type may be used, but positive results require confirmation with a test from the alternate category because false-positive results are common.

Question 4

Tx?

Answer 4

IM benzathine penicillin G

Question 5

Tx with penicillin allergy?

Answer 5

desensitization and then penicillin

Question 6

Preganancy effects (patho)? 2

Answer 6

Intrauterine fetal demise
Preterm labor

Question 7

Fetal effects (patho)? 4

Answer 7

Hepatic (hepatomegaly, jaundice)
Hematologic (hemolytic anemia, decr. PLT)
MSK (long bone abnormalities)
Failure to thrive

Question 8

Due to the superior efficacy of penicillin and severity of syphilis-related fetal complications.

Alternate antibiotic choices, including other forms of penicillin (eg, amoxicillin), are ineffective, are contraindicated, or have limited data in pregnan

Answer 8

.

Question 9

What abs can be given in non-pregnant with allergy?

Answer 9

galima duoti doxycylin, bet NESTUMO METU JIS KONTRAINDIKUOTINAS

Question 10

UW. Congenital syphilis table. CP early. Snuffles?

Answer 10

Copious clear, purulent or serosanguineous rhinorrhea

Question 11

UW. Congenital syphilis table. CP early. Maculopapular rash?

Answer 11

Palms, soles, buttocks, legs usually involved
Desquamation and hyperpigmentation

Question 12

UW. Congenital syphilis table. CP early. MSK?

Answer 12

Long bone abnormalities (eg metaphyseal lucencies)

Question 13

UW. Congenital syphilis table. CP early. Nonspecific findings?

Answer 13

jaundice, hepatosplenomegaly, growth restriction, ,,blueberry muffin” spots.

Question 14

UW. Congenital syphilis table. CP LATE.?

Answer 14

Saddle nose, notched (Hutchinson) teeth, saber shins, sensorineural hearing loss

Question 15

UW. Congenital syphilis table. Dx? serologic

Answer 15

VDLR, RPR

Question 16

UW. Congenital syphilis table. Dx? darkfield microscopy

Answer 16

Treponema pallidum in infectious material (eg nasal discharge, skin lesions, placenta)

Question 17

UW. Congenital syphilis table. Tx?

Answer 17

penicillin

Question 18

UW. Congenital syphilis table. Prevention?

Answer 18

1st trimester maternal screening: repeat if high risk (other prenatal STI)
Prenatal penicillin