UW intrahepatic cholestasis and cholelithiasis 12-18 (1) Flashcards

1
Q

cholestasis. CP. when occurs?

A

in 3rd trimester

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2
Q

cholestasis. CP. pruritus? 3

A

generalized pruritus
pruritus worse on hands and feet
no associated rash

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3
Q

cholestasis. CP. pain?

A

RUQ pain

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4
Q

cholestasis. lab. biles?

A

incr. total bile acids (>10 umol/l)

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5
Q

cholestasis. lab. transaminases?

A

incr. transaminases (<2x normal)

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6
Q

cholestasis. lab. bilirubin?

A

+/- incr. total and direct bilirubin

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7
Q

cholestasis. obstetric risks, 4?

A

intrauterine fetal demise
preterm delivery
meconium-stained amniotic fluid
neonatal respiratory distress syndrome

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8
Q

cholestasis. management? 3

A

delivery at 37 weeks gestation
ursodeoxycholic acid
antihistamines

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9
Q

symptomatic cholelithiasis. patho? 2

A

incr. biliary cholesterol excretion (estrogen)
decr. gallbladdder motility (progesterone)

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10
Q

symptomatic cholelithiasis. patho. what hormone:incr. biliary cholesterol excretion?

A

estrogen

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11
Q

symptomatic cholelithiasis. patho. decr. gallbladdder motility?

A

progesterone

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12
Q

symptomatic cholelithiasis. CP?

A

recurrent, postprandial epigastric/RUQ pain
RUQ UG with echogenic foci (stones or sludge)

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13
Q

symptomatic cholelithiasis. Mx? 2

A

conservative (eg pain control)
Cholecystectomy (for complicated, recurrent cases)

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