Mehl. Vulvovaginal lesions 03-24 (1) Flashcards
M. Vulvovaginal carcinoma. definition?
Cancer of the vagina and/or vulva.
M. Vulvovaginal carcinoma. causes?
Almost always squamous cell carcinoma due to HPV 16 or 18.
Can occur rarely due to lichen sclerosus.
M. Almost always squamous cell carcinoma due to HPV 16 or 18. tumor?
Vulvovaginal carcinoma
M. aka warts; caused by HPV 6/11. tumor?
Condylomata acuminata
M. Condylomata acuminata. causes?
Aka warts; caused by HPV 6/11.
M. Condylomata acuminata. CP?
Present as painless, skin-colored or slightly hyperpigmented cauliflower- like popular lesions.
M. Lichen sclerosus. CP?
Presents as whitish-grey, rough, irritated or scratchy patch on the vulva or perineum.
M. Lichen sclerosus. Cause?
Thought to be caused by a mix of chronic irritation and autoimmunity; not HPV-related.
M. Characterized by atrophy, hyperkeratosis, and a band of lymphocytes in the dermis. It is not neoplasia, dysplasia, or metaplasia. tumor?
Lichen sclerosus
!!! M. Lichen sclerosus. next best step?
USMLE wants biopsy as next best step to rule out SCC. If SCC is negative and the diagnosis is LS, USMLE wants topical steroid as treatment.
M. Lichen sclerosus. Tx?
USMLE wants topical steroid as treatment.
M. Rare as fuck. Rhabdomyosarcoma of the vagina. Seen in pediatrics as bunches of grapes protruding from the vagina. Tumor?
Sarcoma botryoides
M. Sarcoma botryoides. definition? age?
Rare as fuck.
Rhabdomyosarcoma of the vagina.
Seen in pediatrics as bunches of grapes protruding from the vagina.
M. Obscure cancer that occurs in women 30s-50s due to diethylstilbestrol (DES) exposure in their mothers while they were pregnant 30-50 years ago.
Clear cell vaginal carcinoma
M. Clear cell vaginal carcinoma. what patients? cause?
Obscure cancer that occurs in women 30s-50s due to diethylstilbestrol (DES) exposure in their mothers while they were pregnant 30-50 years ago.
M. Shows up as a tender/painful bump at a 4- or 8-o’clock position on the vulva. Name?
Bartholin gland cyst
M. Bartholin gland cyst. when we call it abscess?
If the cyst becomes infected (i.e., warm and red), we call it Bartholin gland abscess.
M. Bartholin gland cyst. most likely mos?
polymicrobal
M. Bartholin gland CYST - Tx?
For cysts, sitz bath + warm compresses are first Tx.
M. Bartholin gland ABSCESS Tx?
drainage is the answer.
M. Vignette will be a child with foul-smelling discharge from the vagina. There will be no signs of physical trauma or lacerations (means not abuse). Name?
Vaginal foreign body
M. Vaginal foreign body. CP?
Vignette will be a child with foul-smelling discharge from the vagina.
There will be no signs of physical trauma or lacerations (means not abuse).
M. Sexual abuse. in what age?
Can occur in children or elderly (I’ve seen both on NBME).
M. Sexual abuse. Vignette likes to mention what?
Lacerations.
There may or may not be discharge.