medchem 1

Question 1

enamtimors have

Answer 1

-Enantomers are steroisomers that cant be superiomposed
- they have opposite configuration
- same physical and chemical properties ( melting , boiling point, density )
- and are active
- different biological activity
- different 3d arrangement

Question 1

chirals molicules have

Answer 1

same chemical properties, unique 3d shape, different biological properties. They are optically active. while achirals are inactive

Question 2

drugs are only

Answer 2

50% active and give rise to two enatomrs and enzymes have only one chiral.

Question 3

d- dexometry and l- lexometry refers to

Answer 3

d: +ve and clockwise
l: -ve and anti clockwise

Question 4

lactic acid is an example of

Answer 4

racemic mixture that’s optically inactive

Question 5

observed rotation depends on

Answer 5

length, concentration, strength of optical activity, temp, and wavelength of light.

Question 6

sodium street light

Answer 6

uses 580nm light and specific rotation is alpha d. ( 10 cm= 1 dm)

Question 7

1 gram dissolved in 20 ml ethanol , 5 ml is placed in a 20 cm tube at 25 degrees. Observed rotation is 1.25 clockwise.

Answer 7

1.25/ ( 20 x 20 cm )
convert ml to later by 0.001
convert cm to dm