MCQ INCORRECT Flashcards

1
Q

nominal aphasia ?
what and where

A

difficult to recall the names of people or objects
- anmgular gyrus = dominant temporoparietal region

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2
Q

which area of brain associated with social valuation?

A

orbitofrontal cortex

you put a ‘front’ on to fit in with your ‘orbit’

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3
Q

where does early alzheimers disease show early change

A

entorhinal cortex (medial temporal lobe)

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4
Q

where are mirror neurones?

A

inferior frontal cortex

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5
Q

Lithium toxicity tremor?
Long term lithium use tremor?

A

Lithium toxicity = Coarse, intention tremor (might have been an INTENTIONAL overdose)

Long term lithium use = Fine, physiological tremor

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6
Q

QTc is prolonged if

A

> 440ms in men or > 460ms in women

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7
Q

Which test designed specifically, to be sensitive to the changes brought on by antidepressants?

A

MADRS (Montgomery–Åsberg Depression Rating Scale

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8
Q

Wilsons = ?copper and ceruplasmin

A

Low serum ceruloplasmin and low serum copper

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9
Q

gut reaction / moral intuition that is experienced when witnessing or considering an event?

A

Ventromedial prefrontal cortex
(gut of pre-frontal coretx)

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10
Q

PYRAMIDINE bases
purine

A

pyramids were CUT from stone (Cystocinem uracil, thymine)
adenine and guanine

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11
Q

where are mirror neurones

A

inferior frontal gyrus
you look in the mirrow IN- FROnt of you
INferior FRONTal

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12
Q

dysfunction in which area leads to disinhibition?

A

orbitofrontal cortex
if youre disinhibited - you can SEE easily theyre acting bizarre = ORBITO-FRONTAL

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13
Q

part of the Default Mode Network and plays a key role in the sense of self?

A

Posterior cingulate cortex.
self-referential thought, memory recall
Think of it as the TAIL of a shrimp - its wondering is it the same as the head of the shrimp? SELF referential and sense of self

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14
Q

connects regions of the frontal lobe with regions of the temporal lobe of the same hemisphere?

A

Superior Longitudinal (arcuate) Fasciculus.

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15
Q

Amphetamine has been shown to result in excessive dopaminergic activity in which of the following areas of the brain thus suggesting a causative role in schizophrenia

A

striatum
- misolimbic system

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16
Q

which hormones increase hunger?

which hormones decrease hunger?

A

increase:
neuropeptide Y (from hypothalamus)
Ghrelin - from stomach

Decrease:
Cholecystokinin from duodenum

Leptin- from adipose tissue

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17
Q

commonly used to treat REM sleep behaviour disorder

A

Clonazepam

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18
Q

EEG effects of lithium?

A

Lithium increased all A B T D

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18
Q

which of the following neuroplastic effects is most reliably observed in patients undergoing ECT?

A

Increased hippocampal volume

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19
Q

nucleus of Meynert is located?

what does it do?

A

substantia innominata of the basal forebrain

main source of Acetylcholine in brain

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20
Q

Long Term potentiation is mediated by

A

glutamate - NMDA receptors

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21
Q

Nictine receptor stimulation can lead to release of what neurotransmitter?

A

Dopamine (think you get a dopamine HIT from smoking)

22
Q

NMDA receptor type?

A

Ionotropic
so is GABA A

23
Q

which neutrotransmitter plays important role in huntingtons disease?

24
cheat hack to determine if X-linked dominiant or AD?
if father to son, cannot be X linked!!
25
conrad 5 stages delusional psychosis
trema- delusional mood apophany- search for new meaning anastrophy- heightening psychosis consolidation = forming new world
26
1st line treatment of clozapine induced constipation?
Senna
27
transition vs transversion genetics?
transition - purine replacedby purine transversion - purine replaced by pyramidine etc
28
genes in schizophrenia?
DIS DISC New? this disc new? DISC1, DYS bindind, neuroregulin
29
best test for set shifting?
Wisconsin cart sorting
30
what category is malingering under icd11? how many categories related to psych in icd11? new change with gender incongruence?
Factors influencing health status or contact with health status 21!! gender incongruence- moved to sexual health chapter
31
- CONSTRUCTIONAL APRAXIA - test?
- intersecting pentagons
32
trail making test
executive function
33
oneieroid state
dream-like disturbances of consciousness - vivid hallucinations, + catatonic symptoms,
34
gene strongly implicated in ADHD
Dopamine 4 receptor gene
35
mutations in progranulin gene cause
FTD /picks (progranulin = picks a pro granny = picks you up from school
36
genetic associated mutation autism?
SHANK (autistic people get shanked as bullie)
37
area increased blood flow in depression?
anterior cingulate cortex
38
biochem findings depressed patients CRH ACTH
raised CRH - corticotrophin releasing hormone blunted ACTH
39
prosopagnosia
inability to recognise face sophie = wisdom pro sop = in front of the wisdom = brain = the face is in front
40
basal ganglia PUTIN will use NUCLEAR weapons to have GLOBAL domination =
putamen + caudate Nucelus + globus pallidus putamen + globus pallidus = lentiform nucelus putamen + caudate nucelus = striatum
41
gerstman
= LEFT ANGULAR GYRUS SYNDROME
42
mood stabiliser that causes kidney stones?
topiromate
43
kohlberg?
KONVENTION CONVENTION
44
psychotic defence mechanism?
DDD! DENIAL DISTORTION DELUSION PROJECTION
45
genetic mutations is most common found in early onset familial Alzheimer's disease?
PSEN 1
46
GENE LINKED APP PSEN 1 P SEN 2 APOE
APP 21 PSEN-1 14 PSEN-2 1 APOE 19
47
LAW OF EFFECT - (WHO?)
Thorndike
48
Alexia without agraphia blood supply cause
posterior cerebral
49
SERETONIN RECEPTOR INVOLVED CIRCADIN RHYTHM?
7 (snow white and 7 dwarves- one of them was sleepy)
50
introduction filter theory
broadbent
51
conduction aphasia?
repitition difficulty - lesion in the arcuate fasciculus.
52
tramadol + SSRI
can cause Seretonin syndrome as also SRNI
53
Sydenham's chorea
rapid, uncoordinated jerking movements affecting primarily the face, feet and hands. infection with Group A beta-hemolytic Streptococci and usually appears 6 months after the infection. rare in adults, resolves after several months.