MCQ INCORRECT Flashcards
nominal aphasia ?
what and where
difficult to recall the names of people or objects
- anmgular gyrus = dominant temporoparietal region
which area of brain associated with social valuation?
orbitofrontal cortex
you put a ‘front’ on to fit in with your ‘orbit’
where does early alzheimers disease show early change
entorhinal cortex (medial temporal lobe)
where are mirror neurones?
inferior frontal cortex
Lithium toxicity tremor?
Long term lithium use tremor?
Lithium toxicity = Coarse, intention tremor (might have been an INTENTIONAL overdose)
Long term lithium use = Fine, physiological tremor
QTc is prolonged if
> 440ms in men or > 460ms in women
Which test designed specifically, to be sensitive to the changes brought on by antidepressants?
MADRS (Montgomery–Åsberg Depression Rating Scale
Wilsons = ?copper and ceruplasmin
Low serum ceruloplasmin and low serum copper
gut reaction / moral intuition that is experienced when witnessing or considering an event?
Ventromedial prefrontal cortex
(gut of pre-frontal coretx)
PYRAMIDINE bases
purine
pyramids were CUT from stone (Cystocinem uracil, thymine)
adenine and guanine
where are mirror neurones
inferior frontal gyrus
you look in the mirrow IN- FROnt of you
INferior FRONTal
dysfunction in which area leads to disinhibition?
orbitofrontal cortex
if youre disinhibited - you can SEE easily theyre acting bizarre = ORBITO-FRONTAL
part of the Default Mode Network and plays a key role in the sense of self?
Posterior cingulate cortex.
self-referential thought, memory recall
Think of it as the TAIL of a shrimp - its wondering is it the same as the head of the shrimp? SELF referential and sense of self
connects regions of the frontal lobe with regions of the temporal lobe of the same hemisphere?
Superior Longitudinal (arcuate) Fasciculus.
Amphetamine has been shown to result in excessive dopaminergic activity in which of the following areas of the brain thus suggesting a causative role in schizophrenia
striatum
- misolimbic system
which hormones increase hunger?
which hormones decrease hunger?
increase:
neuropeptide Y (from hypothalamus)
Ghrelin - from stomach
Decrease:
Cholecystokinin from duodenum
Leptin- from adipose tissue
commonly used to treat REM sleep behaviour disorder
Clonazepam
EEG effects of lithium?
Lithium increased all A B T D
which of the following neuroplastic effects is most reliably observed in patients undergoing ECT?
Increased hippocampal volume
nucleus of Meynert is located?
what does it do?
substantia innominata of the basal forebrain
main source of Acetylcholine in brain
Long Term potentiation is mediated by
glutamate - NMDA receptors
Nictine receptor stimulation can lead to release of what neurotransmitter?
Dopamine (think you get a dopamine HIT from smoking)
NMDA receptor type?
Ionotropic
so is GABA A
which neutrotransmitter plays important role in huntingtons disease?
GABA
cheat hack to determine if X-linked dominiant or AD?
if father to son, cannot be X linked!!
conrad 5 stages delusional psychosis
trema- delusional mood
apophany- search for new meaning
anastrophy- heightening psychosis
consolidation = forming new world
1st line treatment of clozapine induced constipation?
Senna
transition vs transversion genetics?
transition - purine replacedby purine
transversion - purine replaced by pyramidine etc
genes in schizophrenia?
DIS DISC New?
this disc new?
DISC1, DYS bindind, neuroregulin
best test for set shifting?
Wisconsin cart sorting
what category is malingering under icd11?
how many categories related to psych in icd11?
new change with gender incongruence?
Factors influencing health status or contact with health status
21!!
gender incongruence- moved to sexual health chapter
- CONSTRUCTIONAL APRAXIA - test?
- intersecting pentagons
trail making test
executive function
oneieroid state
dream-like disturbances of consciousness - vivid hallucinations, + catatonic symptoms,
gene strongly implicated in ADHD
Dopamine 4 receptor gene
mutations in progranulin gene cause
FTD /picks
(progranulin = picks
a pro granny = picks you up from school
genetic associated mutation autism?
SHANK
(autistic people get shanked as bullie)
area increased blood flow in depression?
anterior cingulate cortex
biochem findings depressed patients
CRH
ACTH
raised CRH - corticotrophin releasing hormone
blunted ACTH
prosopagnosia
inability to recognise face
sophie = wisdom
pro sop = in front of the wisdom = brain = the face is in front
basal ganglia
PUTIN will use NUCLEAR weapons to have GLOBAL domination =
putamen + caudate Nucelus + globus pallidus
putamen + globus pallidus = lentiform nucelus
putamen + caudate nucelus = striatum
gerstman
= LEFT ANGULAR GYRUS SYNDROME
