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MRPSYCH PART A > BASIC PHARMACOLOGY > Flashcards

BASIC PHARMACOLOGY Flashcards

1
Q

FGA vs SGA

A

second generation came into use after 1990

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2
Q

4 types of new novel antipsychotics?

A
  1. Xanomeline (m1/m4 central agonism)
  2. Roluperidone - 5Ht2A antagonist- help -ve syx
  3. D3 Antagonists
  4. Trace amine receptor antagonisnt
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3
Q

placebo vs nocebo

A

placebo - beneficial outcomes
nocebo - harmful outcomes

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4
Q

placebo induced analgesia is partially reversed by

A

administering the opioid antagonist naloxone

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5
Q
A
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5
Q

median toxic dose

median effective dose

A

Dose at which 50% of patients experience a specific toxic effect

dost at which 50% have specified therapeutic effect

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5
Q

Quantal curves

Dose response curves

A

Plot the % of a population showing a specified, predefined categorical drug effect against the dose

Dose response curves- plot the drug concentration against continuous effect of the drug

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MRPSYCH PART A (21 decks)

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