May1 M3-CNS Infections Flashcards
classification of meningitis
- bacterial (community acquired OR healthcare-associated/post-neurosurgical)
- viral
- fungal
- mycobacterial
- parasitic
(imp?) most common bacterial pathogen for meningitis in neonates IN THE COMMUNITY (<1 month of age)
GEL
- GBS (agalactiae), transmitted vertically intrapartum*
- enterobacteriaceae
- listeria (rare now)
(imp?) most common bacterial pathogen for meningitis in 1-23 months old babies (>1, <24) IN THE COMMUNITY
strep pneumoniae
(imp?) most common bacterial pathogen for meningitis in 2-50 year old people IN THE COMMUNITY
strep pneumo (also Neisseria)
(imp?) most common bacterial pathogen for meningitis in people over 50 years of age
- strep pneumo *
- Neisseria
- Listeria* (comes back)
- strep pneumo *
pathogen with important mortality in meningitis
Neisseria meningitidis
who’s especially susceptible for Neisseria meningitidis infections
C5-C9 (MAC) complement deficiencies patients. vulnerable to encapsulated organisms in general (S pneumo, N mening, haemophilus influenza)
classical organisms that are encapsulated
- Strep pneumo
- N mening
- Haemophilus influenza
(important) spleen removed = at risk for what infections (what type of meningitis) #1 and #2
encapsulated organisms
- strep pneumo (#1)
- neisseria meningitidis (#2)
- haemophilus influenza
(important) how bacterial meningitis organisms are transmitted
by droplets
how do you get listeria monocytogenes infection (and meningitis)
from contaminated foods
(imp?) conditions that increase risk of listeriosis (listeria infection and meningitis)
- iron overload conditions (like hemochromatosis)
- immunodeficiency conditions (neonates, old, pregnant, etc.)
(imp?) listeriosis affects what group especially
pregnant women because of immunodeficiency
pathogens in HOSPITAL associated bacterial meningitis
- aerobic gram- bacilli like pseudomonas is 40% of cases
- staph aureus and CoNS (epidermidis, etc.)
- propionibacterium acnes (on plastic devices)
what viruses cause the majority of viral meningitis
enteroviruses (echoviruses, coxsackie viruses)