May 2nd Flashcards
What are the clinical features of Felty syndrome?
RA, neutropenia, splenomegaly
How is Felty syndrome diagnosed?
Anti-CCP and RF are positive, increased ESR, peripheral smear and bone marrow bx to r/o other causes
Eyelid xanthelasma is associated with what biliary disease?
Primary biliary cholangitis
What is a pharmacological therapy for primary biliary cholangitis?
Ursodeoxycholic acid
What is the most common cause of death in dialysis patients?
CVD - 20% MI, 60% sudden cardiac death
Beriberi results in what type of cardiomyopathy?
Dilated cardiomyopathy
Concentric LV hypertrophy is seen in what cardiomyopathy?
Restrictive cardiomyopathy
What are the causes of restrictive cardiomyopathy?
Infiltrative (eg sarcoid, amyloid), storage disease (hemochromatosis) or endomyocardial fibrosis, idiopathic
What drugs can cause folate deficiency?
MTX (supplement with leucovorin), TMP, and phenytoin (decreased absorption in gut)
What are the clinical features of mycoplasma pneumoniae?
HA, malaise, fever, and INCESSANT DRY COUGH; can have pharyngitis and macular/vesicular rash; subclinical hemolytic anemia (cold agglutinins), WBC usually normal
Patient with SOB, cough, dullness to percussion with increased breath sounds
Lobar pneumonia causing lung consolidation
Dimorphic RBCs, increased serum iron concentration and decreased TIBC in patient receiving RIPE therapy
Sideroblastic anemia due to pyridoxine def resulting in impairment of protoporphyrin synthesis
What are the clinical manifestations of chronic arsenic toxicity?
Sensorimotor neuropathy with burning and painful hypersensitivity in stocking glove distribution, distal weakness, hyporeflexia, hypo- and hyper-pigmentation of the skin (earlier) and hyperkeratosis and scaling of the soles and palms (later); can also see Mees lines (horizontal striation of fingernails)
What is the treatment for arsenic poisoning?
Dimercaprol and DMSA
What is a nonstress test fetal surveillance?
External fetal HR monitoring
