May 21st Flashcards
Renal angiomyolipoma is associated with what genetic disease?
Tuberous sclerosis
Child with abdominal pain and purpuric rash on lower extremities and arthralgia
Think Henoch-Schonlein Purpura; IgA mediated leukocytoclastic vasculitis
What laboratory findings are seen in Henoch-Schonlein Purpura?
Normal plts, normal coags, normal to elevated Cr, hematuria + proteinuria
What is the treatment for Henoch Schonlein purpura?
Supportive, NSAIDs, if severe steroids
What is lung compliance?
Ability of lungs to expand
What pathophysiology is seen in ARDS?
V/Q mismatch; lung compliance (ability to expand) is decreased (stiff lungs) due to both loss of surfactant and increased elastic recoil of edematous lungs; pulm art pressure increased (PHTN) due to hypoxic vasoconstriction
What is attributable risk percentage?
Represents the excess risk in a population that can be explained by exposure to a particular risk factor
What is the calculation for attributable risk percentage using RR?
ARP = (RR-1)/RR
what respiratory changes are seen in pregnancy?
Increased ventilation due to increased TV and increased minute ventilation; results in chronic respiratory alkalosis with increased PaO2 (100-110); all due to progesterone
In a case control study what is the main measure of association?
Exposure odds ratio
What is the proper protocol for post-exposure prophylaxis to HIV?
Immediate serology; serology at 6 weeks, 3 months, and 6 months; and triple drug therapy (tenofovir-emtracitabine with raltegravir preferred; ie 2 NRTIs + integrase inhibitor); PEP x 4 weeks
What is the adverse effect of hydroxychloroquine?
Retinal toxicity; baseline ophthalmologic exam with annual reassessment beginning after 5 years
What are the adverse effects of MTX?
Liver tox, pulm fibrosis, stomatitis, bone marrow suppression
What is a normal Rinne test? An abnormal Rinne test means what?
Normal: AC > BC ; abnormal BC > AC (hear it more on mastoid vs EAC), abnormal means conductive hearing loss
In conductive hearing loss, the Weber test results in what?
Lateralization to affected ear
What is the etiology and treatment for endometritis?
Polymicrobial; clindamycin & gentamicin
